Lineage for d2rfna_ (2rfn A:)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2542179Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2542180Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2542316Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2543916Protein Hepatocyte growth factor receptor, c-MET [103300] (1 species)
    PTK group; HGFR subfamily; membrane spanning protein tyrosine kinase
  7. 2543917Species Human (Homo sapiens) [TaxId:9606] [103301] (57 PDB entries)
  8. 2543965Domain d2rfna_: 2rfn A: [168088]
    automated match to d1r0pa_
    complexed with am7

Details for d2rfna_

PDB Entry: 2rfn (more details), 2.5 Å

PDB Description: x-ray structure of c-Met with inhibitor.
PDB Compounds: (A:) Hepatocyte growth factor receptor

SCOPe Domain Sequences for d2rfna_:

Sequence, based on SEQRES records: (download)

>d2rfna_ d.144.1.7 (A:) Hepatocyte growth factor receptor, c-MET {Human (Homo sapiens) [TaxId: 9606]}
alnpelvqavqhvvigpsslivhfnevigrghfgcvyhgtlldndgkkihcavkslnrit
digevsqfltegiimkdfshpnvlsllgiclrsegsplvvlpymkhgdlrnfirnethnp
tvkdligfglqvakgmkylaskkfvhrdlaarncmldekftvkvadfglardmydkeyys
vhnktgaklpvkwmaleslqtqkfttksdvwsfgvllwelmtrgappypdvntfditvyl
lqgrrllqpeycpdplyevmlkcwhpkaemrpsfselvsrisaifstfigehyvh

Sequence, based on observed residues (ATOM records): (download)

>d2rfna_ d.144.1.7 (A:) Hepatocyte growth factor receptor, c-MET {Human (Homo sapiens) [TaxId: 9606]}
alnpelvqavqhvvigpsslivhfnevifgcvyhgtlldndgkkihcavkslnritdige
vsqfltegiimkdfshpnvlsllgiclrsegsplvvlpymkhgdlrnfirnethnptvkd
ligfglqvakgmkylaskkfvhrdlaarncmldekftvkvadpvkwmaleslqtqkfttk
sdvwsfgvllwelmtrgappypdvntfditvyllqgrrllqpeycpdplyevmlkcwhpk
aemrpsfselvsrisaifstfigehyvh

SCOPe Domain Coordinates for d2rfna_:

Click to download the PDB-style file with coordinates for d2rfna_.
(The format of our PDB-style files is described here.)

Timeline for d2rfna_: