SCOPe 2.07: Domain d2rexd_: 2rex D:

Lineage for d2rexd_ (2rex D:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (80 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein automated matches [190047] (34 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [186768] (286 PDB entries)

8. Domain d2rexd_: 2rex D: [168069]
   Other proteins in same PDB: d2rexa_, d2rexc_
   automated match to d1gwna_
   complexed with ca, gnp, mg, unx

Details for d2rexd_

PDB Entry: 2rex, 2.3 Å

PDB Description: crystal structure of the effector domain of plxnb1 bound with rnd1 gtpase

PDB Compounds: (D:) rho-related GTP-binding protein rho6

SCOPe Domain Sequences for d2rexd_:

Sequence, based on SEQRES records:

>d2rexd_ c.37.1.8 (D:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
pqpvvarcklvlvgdvqcgktamlqvlakdcypetyvptvfenytacleteeqrvelslw
dtsgspyydnvrplcysdsdavllcfdisrpetvdsalkkwrteildycpstrvlligck
tdlrtdlstlmelshqkqapisyeqgcaiakqlgaeiylegsaftseksihsifrtasml
cl

Sequence, based on observed residues (ATOM records):

>d2rexd_ c.37.1.8 (D:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
pqpvvarcklvlvgdvqcgktamlqvlakdcypetyvptvfenytacleteeqrvelslw
dtsgspyydnvrplcysdsdavllcfdisrpetvalkkwrteildycpstrvlligcktd
lrtdlstlmelshqkqapisyeqgcaiakqlgaeiylegsaftseksihsifrtasmlcl

Timeline for d2rexd_:

• d2rexd_ first appeared in SCOPe 2.01
  
• d2rexd_ appears in SCOPe 2.06
  
• d2rexd_ appears in the current release, SCOPe 2.08