SCOPe 2.06: Domain d2rd4a_: 2rd4 A:

Lineage for d2rd4a_ (2rd4 A:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.133: Phospholipase A2, PLA2 [48618] (1 superfamily)
   common core: 2 helices, disulfide-linked, and a calcium-binding loop

4. Superfamily a.133.1: Phospholipase A2, PLA2 [48619] (4 families)

5. Family a.133.1.2: Vertebrate phospholipase A2 [48623] (3 proteins)
   automatically mapped to Pfam PF00068

6. Protein Snake phospholipase A2 [48624] (38 species)

7. Species Andaman cobra (Naja sagittifera), isoform 2 [TaxId:195058] [89169] (4 PDB entries)
   heterodimer of two different isoforms

8. Domain d2rd4a_: 2rd4 A: [168052]
   automated match to d1s6ba_
   complexed with ca

Details for d2rd4a_

PDB Entry: 2rd4, 2.97 Å

PDB Description: design of specific inhibitors of phospholipase a2: crystal structure of the complex of phospholipase a2 with pentapeptide leu-val-phe-phe- ala at 2.9 a resolution

PDB Compounds: (A:) Phospholipase A2 isoform 1

SCOPe Domain Sequences for d2rd4a_:

Sequence; same for both SEQRES and ATOM records:

>d2rd4a_ a.133.1.2 (A:) Snake phospholipase A2 {Andaman cobra (Naja sagittifera), isoform 2 [TaxId: 195058]}
ntyqfknmiqctvpkrswwdfadygcycgrggsgtpiddldrccqvhdncynsareqggc
rpkqktysyeckagtlscsgsnnscaatvcdcdrlaaicfagapyndnnynidlkarcq

Timeline for d2rd4a_:

• d2rd4a_ first appeared in SCOPe 2.01
  
• d2rd4a_ appears in SCOPe 2.05
  
• d2rd4a_ appears in SCOPe 2.07
  
• d2rd4a_ appears in the current release, SCOPe 2.08