SCOPe 2.01: Domain d2rb4a_: 2rb4 A:

Lineage for d2rb4a_ (2rb4 A:)

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (25 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.19: Tandem AAA-ATPase domain [81268] (24 proteins)
   duplication: tandem repeat of two RecA-like (AAA) domains

6. Protein ATP-dependent RNA helicase DDX25 [142310] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [142311] (1 PDB entry)
   Uniprot Q9UHL0 307-474

8. Domain d2rb4a_: 2rb4 A: [168041]
   automated match to d2g2ja1
   complexed with cl, so4, zn

Details for d2rb4a_

PDB Entry: 2rb4, 2.8 Å

PDB Description: crystal structure of the helicase domain of human ddx25 rna helicase

PDB Compounds: (A:) ATP-dependent RNA helicase DDX25

SCOPe Domain Sequences for d2rb4a_:

Sequence, based on SEQRES records:

>d2rb4a_ c.37.1.19 (A:) ATP-dependent RNA helicase DDX25 {Human (Homo sapiens) [TaxId: 9606]}
ltlnnirqyyvlcehrkdkyqalcniygsitigqaiifcqtrrnakwltvemiqdghqvs
llsgeltveqrasiiqrfrdgkekvlittnvcargidvkqvtivvnfdlpvkqgeepdye
tylhrigrtgrfgkkglafnmievdelpslmkiqdhfnssikqlnaedmd

Sequence, based on observed residues (ATOM records):

>d2rb4a_ c.37.1.19 (A:) ATP-dependent RNA helicase DDX25 {Human (Homo sapiens) [TaxId: 9606]}
ltlnnirqyyvlcehrkdkyqalcniygsitigqaiifcqtrrnakwltvemiqdghqvs
llsgeltveqrasiiqrfrdgkekvlittnvcargidvkqvtivvnfdlpvgeepdyety
lhrigrtkkglafnmievdelpslmkiqdhfnssikqlnaedmd

Timeline for d2rb4a_:

• d2rb4a_ is new in SCOPe 2.01-stable
  
• d2rb4a_ appears in SCOPe 2.02
  
• d2rb4a_ appears in the current release, SCOPe 2.08