SCOPe 2.07: Domain d2qzob_: 2qzo B:

Lineage for d2qzob_ (2qzo B:)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Estrogen receptor alpha [48519] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48520] (71 PDB entries)
   Uniprot P03372 307-551

8. Domain d2qzob_: 2qzo B: [167893]
   automated match to d1qkua_
   protein/DNA complex; complexed with kn1

Details for d2qzob_

PDB Entry: 2qzo, 1.72 Å

PDB Description: crystal structure of the estrogen receptor alpha ligand binding domain complexed with way-169916

PDB Compounds: (B:) Estrogen receptor

SCOPe Domain Sequences for d2qzob_:

Sequence, based on SEQRES records:

>d2qzob_ a.123.1.1 (B:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
lalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvp
gfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveif
dmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdt
lihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplsdlllemld
ahrl

Sequence, based on observed residues (ATOM records):

>d2qzob_ a.123.1.1 (B:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
lalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvp
gfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveif
dmllatssrfrmmnlqgeefvclksiillnsgvytfleekdhihrvldkitdtlihlmak
agltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplsdlllemldahrl

Timeline for d2qzob_:

• d2qzob_ first appeared in SCOPe 2.01
  
• d2qzob_ appears in SCOPe 2.06