SCOPe 2.02: Domain d2qyka_: 2qyk A:

Lineage for d2qyka_ (2qyk A:)

1. Root: SCOPe 2.02

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
   multihelical; consists of two different alpha-helical bundles

4. Superfamily a.211.1: HD-domain/PDEase-like [109604] (6 families)

5. Family a.211.1.2: PDEase [48548] (7 proteins)
   Pfam PF00233; multihelical; can be divided into three subdomains

6. Protein automated matches [190370] (1 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187208] (9 PDB entries)

8. Domain d2qyka_: 2qyk A: [167884]
   automated match to d1oyna_
   complexed with mg, npv, zn

Details for d2qyka_

PDB Entry: 2qyk, 2.1 Å

PDB Description: Crystal structure of PDE4A10 in complex with inhibitor NPV

PDB Compounds: (A:) Cyclic AMP-specific phosphodiesterase HSPDE4A10

SCOPe Domain Sequences for d2qyka_:

Sequence; same for both SEQRES and ATOM records:

>d2qyka_ a.211.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mniprfgvktdqeellaqelenlnkwglnifcvsdyaggrsltcimymifqerdllkkfr
ipvdtmvtymltledhyhadvayhnslhaadvlqsthvllatpaldavftdleilaalfa
aaihdvdhpgvsnqflintnselalmyndesvlenhhlavgfkllqedncdifqnlskrq
rqslrkmvidmvlatdmskhmtlladlktmvetkkvtssgvllldnysdriqvlrnmvhc
adlsnptkplelyrqwtdrimaeffqqgdrerergmeispmcdkhtasveksqvgfidyi
vhplwetwadlvhpdaqeildtlednrdwyysai

Timeline for d2qyka_:

• d2qyka_ first appeared in SCOPe 2.01
  
• d2qyka_ appears in SCOPe 2.03
  
• d2qyka_ appears in the current release, SCOPe 2.08, called d2qyka1