SCOPe 2.07: Domain d2qsea_: 2qse A:

Lineage for d2qsea_ (2qse A:)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Estrogen receptor alpha [48519] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48520] (82 PDB entries)
   Uniprot P03372 307-551

8. Domain d2qsea_: 2qse A: [167792]
   automated match to d1qkua_
   protein/DNA complex; complexed with 1hp

Details for d2qsea_

PDB Entry: 2qse, 1.85 Å

PDB Description: crystal structure of the estrogen receptor alpha ligand binding domain complexed with burned meat compound 4-oh-phip

PDB Compounds: (A:) Estrogen receptor

SCOPe Domain Sequences for d2qsea_:

Sequence, based on SEQRES records:

>d2qsea_ a.123.1.1 (A:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
slalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrv
pgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmvei
fdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitd
tlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplsdllleml
dahrl

Sequence, based on observed residues (ATOM records):

>d2qsea_ a.123.1.1 (A:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
slalsltadqmvsalldaeppilyserpfseasmmglltnladrelvhminwakrvpgfv
dltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrncvegmveifdmllat
ssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdtlihlma
kagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplsdlllemldahrl

Timeline for d2qsea_:

• d2qsea_ first appeared in SCOPe 2.01
  
• d2qsea_ appears in SCOPe 2.06
  
• d2qsea_ appears in the current release, SCOPe 2.08