SCOPe 2.07: Domain d2qe4b_: 2qe4 B:

Lineage for d2qe4b_ (2qe4 B:)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Estrogen receptor alpha [48519] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48520] (82 PDB entries)
   Uniprot P03372 307-551

8. Domain d2qe4b_: 2qe4 B: [167558]
   automated match to d1qkta_
   protein/DNA complex; complexed with jj3

Details for d2qe4b_

PDB Entry: 2qe4, 2.4 Å

PDB Description: estrogen receptor alpha ligand-binding domain in complex with a benzopyran agonist

PDB Compounds: (B:) Estrogen receptor

SCOPe Domain Sequences for d2qe4b_:

Sequence, based on SEQRES records:

>d2qe4b_ a.123.1.1 (B:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
lalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvp
gfvdltlhdqvhllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmveif
dmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdt
lihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysm

Sequence, based on observed residues (ATOM records):

>d2qe4b_ a.123.1.1 (B:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
lalsltadqmvsalldaeppilysesmmglltnladrelvhminwakrvpgfvdltlhdq
vhllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmveifdmllatssrf
rmmnlqgeefvclksiillnsgvytfekdhihrvldkitdtlihlmakagltlqqqhqrl
aqlllilshirhmsnkgmehlysm

Timeline for d2qe4b_:

• d2qe4b_ first appeared in SCOPe 2.01
  
• d2qe4b_ appears in SCOPe 2.06
  
• d2qe4b_ appears in the current release, SCOPe 2.08