SCOPe 2.08: Domain d2qe4a_: 2qe4 A:

Lineage for d2qe4a_ (2qe4 A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Estrogen receptor alpha [48519] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48520] (107 PDB entries)
   Uniprot P03372 307-551

8. Domain d2qe4a_: 2qe4 A: [167557]
   automated match to d1qkta_
   protein/DNA complex; complexed with jj3

Details for d2qe4a_

PDB Entry: 2qe4, 2.4 Å

PDB Description: estrogen receptor alpha ligand-binding domain in complex with a benzopyran agonist

PDB Compounds: (A:) Estrogen receptor

SCOPe Domain Sequences for d2qe4a_:

Sequence, based on SEQRES records:

>d2qe4a_ a.123.1.1 (A:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
lalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvp
gfvdltlhdqvhllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmveif
dmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdt
lihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysm

Sequence, based on observed residues (ATOM records):

>d2qe4a_ a.123.1.1 (A:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
lalsltadqmvsalldaeppilysepfseasmmglltnladrelvhminwakrvpgfvdl
tlhdqvhllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmveifdmlla
tssrfrmmnlqgeefvclksiillnsgvytkdhihrvldkitdtlihlmakagltlqqqh
qrlaqlllilshirhmsnkgmehlysm

Timeline for d2qe4a_:

• d2qe4a_ first appeared in SCOPe 2.01
  
• d2qe4a_ appears in SCOPe 2.07