Lineage for d2q7ka_ (2q7k A:)

  1. Root: SCOPe 2.08
  2. 2685877Class a: All alpha proteins [46456] (290 folds)
  3. 2728284Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
    multihelical; 3 layers or orthogonally packed helices
  4. 2728285Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families) (S)
  5. 2728286Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)
  6. 2728287Protein Androgen receptor [63621] (4 species)
  7. 2728297Species Human (Homo sapiens) [TaxId:9606] [63623] (65 PDB entries)
    Uniprot P10275 671-919
  8. 2728304Domain d2q7ka_: 2q7k A: [167462]
    automated match to d1e3ga_
    complexed with gol, so4, tes; mutant

Details for d2q7ka_

PDB Entry: 2q7k (more details), 1.8 Å

PDB Description: the androgen receptor prostate cancer mutant h874y ligand binding domain bound with testosterone and an ar 20-30 peptide
PDB Compounds: (A:) Androgen receptor

SCOPe Domain Sequences for d2q7ka_:

Sequence, based on SEQRES records: (download)

>d2q7ka_ a.123.1.1 (A:) Androgen receptor {Human (Homo sapiens) [TaxId: 9606]}
piflnvleaiepgvvcaghdnnqpdsfaallsslnelgerqlvhvvkwakalpgfrnlhv
ddqmaviqyswmglmvfamgwrsftnvnsrmlyfapdlvfneyrmhksrmysqcvrmrhl
sqefgwlqitpqeflcmkalllfsiipvdglknqkffdelrmnyikeldriiackrknpt
scsrrfyqltklldsvqpiarelyqftfdllikshmvsvdfpemmaeiisvqvpkilsgk
vkpiyfhtq

Sequence, based on observed residues (ATOM records): (download)

>d2q7ka_ a.123.1.1 (A:) Androgen receptor {Human (Homo sapiens) [TaxId: 9606]}
piflnvleaiepgvvcaghdnnqpdsfaallsslnelgerqlvhvvkwakalpgfrnlhv
ddqmaviqyswmglmvfamgwrsftnvnsrmlyfapdlvfneyrmhksrmysqcvrmrhl
sqefgwlqitpqeflcmkalllfsiipvdglknqkffdelrmnyikeldriiascsrrfy
qltklldsvqpiarelyqftfdllikshmvsvdfpemmaeiisvqvpkilsgkvkpiyfh
tq

SCOPe Domain Coordinates for d2q7ka_:

Click to download the PDB-style file with coordinates for d2q7ka_.
(The format of our PDB-style files is described here.)

Timeline for d2q7ka_: