SCOPe 2.05: Domain d2pppa_: 2ppp A:

Lineage for d2pppa_ (2ppp A:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.26: FKBP-like [54533] (3 superfamilies)
   core: beta(2)-alpha-beta(2); antiparallel beta-sheet

4. Superfamily d.26.1: FKBP-like [54534] (4 families)

5. Family d.26.1.1: FKBP immunophilin/proline isomerase [54535] (17 proteins)

6. Protein FK-506 binding protein (FKBP12), an immunophilin [54536] (2 species)
   cis-trans prolyl-isomerase

7. Species Human (Homo sapiens) [TaxId:9606] [54537] (42 PDB entries)

8. Domain d2pppa_: 2ppp A: [167237]
   automated match to d1a7xa_
   mutant

Details for d2pppa_

PDB Entry: 2ppp, 0.94 Å

PDB Description: crystal structure of e60q mutant of fkbp12

PDB Compounds: (A:) FK506-binding protein 1A

SCOPe Domain Sequences for d2pppa_:

Sequence; same for both SEQRES and ATOM records:

>d2pppa_ d.26.1.1 (A:) FK-506 binding protein (FKBP12), an immunophilin {Human (Homo sapiens) [TaxId: 9606]}
gvqvetispgdgrtfpkrgqtcvvhytgmledgkkfdssrdrnkpfkfmlgkqevirgwq
egvaqmsvgqrakltispdyaygatghpgiipphatlvfdvellkle

Timeline for d2pppa_:

• d2pppa_ first appeared in SCOPe 2.01
  
• d2pppa_ appears in SCOPe 2.04
  
• d2pppa_ appears in SCOPe 2.06
  
• d2pppa_ appears in the current release, SCOPe 2.08