Lineage for d2p3aa_ (2p3a A:)

  1. Root: SCOPe 2.03
  2. 1287432Class b: All beta proteins [48724] (174 folds)
  3. 1320913Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 1320914Superfamily b.50.1: Acid proteases [50630] (4 families) (S)
  5. 1320915Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 proteins)
    dimer of identical mono-domain chains, each containing (6,10) barrel
  6. 1320931Protein Human immunodeficiency virus type 1 protease [50632] (8 species)
  7. 1321128Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (421 PDB entries)
    Uniprot P35963 57-155 ! Uniprot P04587 69-167 ! Uniprot P03366 69-167 ! Uniprot P03367 69-167 ! Uniprot P03368 69-167
  8. 1321433Domain d2p3aa_: 2p3a A: [166991]
    automated match to d1sgua_
    complexed with 3tl; mutant

Details for d2p3aa_

PDB Entry: 2p3a (more details), 1.75 Å

PDB Description: crystal structure of the multi-drug resistant mutant subtype b hiv protease complexed with tl-3 inhibitor
PDB Compounds: (A:) Protease

SCOPe Domain Sequences for d2p3aa_:

Sequence; same for both SEQRES and ATOM records: (download)

>d2p3aa_ b.50.1.1 (A:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 [TaxId: 11676]}
pqitlwkrplvtikiggqlkealldtgaddtvleemalpgkwkprmiggiggfvkvrqyd
qipieicghkvigtvlvgptpaniigrnlmtqigctlnf

SCOPe Domain Coordinates for d2p3aa_:

Click to download the PDB-style file with coordinates for d2p3aa_.
(The format of our PDB-style files is described here.)

Timeline for d2p3aa_: