Lineage for d2p2ha_ (2p2h A:)

  1. Root: SCOPe 2.03
  2. 1396887Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 1433536Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1433537Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1433619Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1435582Protein Vascular endothelial growth factor receptor 2 (kdr) [56160] (1 species)
    PTK group; PDGFR/VEGFR subfamily; membrane spanning protein tyrosine kinase
  7. 1435583Species Human (Homo sapiens) [TaxId:9606] [56161] (20 PDB entries)
  8. 1435587Domain d2p2ha_: 2p2h A: [166956]
    automated match to d1vr2a_
    complexed with 994

Details for d2p2ha_

PDB Entry: 2p2h (more details), 1.95 Å

PDB Description: crystal structure of the vegfr2 kinase domain in complex with a pyridinyl-triazine inhibitor
PDB Compounds: (A:) Vascular endothelial growth factor receptor 2

SCOPe Domain Sequences for d2p2ha_:

Sequence, based on SEQRES records: (download)

>d2p2ha_ d.144.1.7 (A:) Vascular endothelial growth factor receptor 2 (kdr) {Human (Homo sapiens) [TaxId: 9606]}
ehaerlpydaskwefprdrlklgkplgrgafgqvieadafgidktatcrtvavkmlkega
thsehralmselkilihighhlnvvnllgactkpggplmvitefckfgnlstylrskrne
fvpykvapedlykdfltlehlicysfqvakgmeflasrkcihrdlaarnillseknvvki
cdfglardiykdpdyvrkgdarlplkwmapetifdrvytiqsdvwsfgvllweifslgas
pypgvkideefcrrlkegtrmrapdyttpemyqtmldcwhgepsqrptfselvehlgnll
qanaqqdrhhh

Sequence, based on observed residues (ATOM records): (download)

>d2p2ha_ d.144.1.7 (A:) Vascular endothelial growth factor receptor 2 (kdr) {Human (Homo sapiens) [TaxId: 9606]}
ehaerlpydaskwefprdrlklgkplgrqvieadafgidktatcrtvavkmlkegathse
hralmselkilihighhlnvvnllgactkpggplmvitefckfgnlstylrskrnefvpy
kvapedlykdfltlehlicysfqvakgmeflasrkcihrdlaarnillseknvvkicdfg
larlplkwmapetifdrvytiqsdvwsfgvllweifslgaspypgvkideefcrrlkegt
rmrapdyttpemyqtmldcwhgepsqrptfselvehlgnllqanaqqdrhhh

SCOPe Domain Coordinates for d2p2ha_:

Click to download the PDB-style file with coordinates for d2p2ha_.
(The format of our PDB-style files is described here.)

Timeline for d2p2ha_: