SCOPe 2.08: Domain d2orpa1: 2orp A:114-498

Lineage for d2orpa1 (2orp A:114-498)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.174: Nitric oxide (NO) synthase oxygenase domain [56511] (1 superfamily)
   unusual fold

4. Superfamily d.174.1: Nitric oxide (NO) synthase oxygenase domain [56512] (1 family)
   automatically mapped to Pfam PF02898

5. Family d.174.1.1: Nitric oxide (NO) synthase oxygenase domain [56513] (2 proteins)

6. Protein Nitric oxide (NO) synthase oxygenase domain [56514] (6 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [56515] (43 PDB entries)
   Uniprot P29477 77-496 ! Uniprot P29477 77-495

8. Domain d2orpa1: 2orp A:114-498 [166831]
   Other proteins in same PDB: d2orpa2
   automated match to d1nosa_
   complexed with hem, r86
   missing some secondary structures that made up less than one-third of the common domain

Details for d2orpa1

PDB Entry: 2orp, 1.97 Å

PDB Description: Murine inducible nitric oxide synthase oxygenase domain (delta 114) 2-[4-(2-Imidazol-1-yl-6-methyl-pyrimidin-4-yl)-1-isobutyryl-piperazin-2-yl]-N-[2-(4-methoxy-phenyl)-ethyl]-acetamide complex

PDB Compounds: (A:) Nitric oxide synthase, inducible

SCOPe Domain Sequences for d2orpa1:

Sequence, based on SEQRES records:

>d2orpa1 d.174.1.1 (A:114-498) Nitric oxide (NO) synthase oxygenase domain {Mouse (Mus musculus) [TaxId: 10090]}
mnpksltrgprdkptpleellphaiefinqyygsfkeakieehlarleavtkeiettgty
qltldelifatkmawrnaprcigriqwsnlqvfdarncstaqemfqhicrhilyatnngn
irsaitvfpqrsdgkhdfrlwnsqliryagyqmpdgtirgdaatleftqlcidlgwkpry
grfdvlplvlqadgqdpevfeippdlvlevtmehpkyewfqelglkwyalpavanmllev
gglefpacpfngwymgteigvrdfcdtqrynileevgrrmglethtlaslwkdravtein
vavlhsfqkqnvtimdhhtasesfmkhmqneyrarggcpadwiwlvppvsgsitpvfhqe
mlnyvlspfyyyqiepwkthiwqne

Sequence, based on observed residues (ATOM records):

>d2orpa1 d.174.1.1 (A:114-498) Nitric oxide (NO) synthase oxygenase domain {Mouse (Mus musculus) [TaxId: 10090]}
mnpksltrgprdkptpleellphaiefinqyygsfkeakieehlarleavtkeiettgty
qltldelifatkmawrnaprcigriqwsnlqvfdarncstaqemfqhicrhilyatnngn
irsaitvfpqrsdgkhdfrlwnsqliryagyqmpdgtirgdaatleftqlcidlgwkpry
grfdvlplvlqadgqdpevfeippdlvlevtmelglkwyalpavanmllevgglefpacp
fngwymgteigvvlhsfqkqnvtimdhhtasesfmkhmqneyvlspfyyyqiepwkthiw
qne

Timeline for d2orpa1:

• d2orpa1 first appeared in SCOPe 2.01, called d2orpa_
  
• d2orpa1 appears in SCOPe 2.07