SCOPe 2.08: Domain d2oo8x_: 2oo8 X:

Lineage for d2oo8x_ (2oo8 X:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (850 PDB entries)

8. Domain d2oo8x_: 2oo8 X: [166807]
   automated match to d1fvra_
   complexed with raj

Details for d2oo8x_

PDB Entry: 2oo8, 2.2 Å

PDB Description: Synthesis, Structural Analysis, and SAR Studies of Triazine Derivatives as Potent, Selective Tie-2 Inhibitors

PDB Compounds: (X:) Angiopoietin-1 receptor

SCOPe Domain Sequences for d2oo8x_:

Sequence, based on SEQRES records:

>d2oo8x_ d.144.1.7 (X:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
gqvlkarikkdglrmdaaikrmkeyaskddhrdfagelevlcklghhpniinllgacehr
gylylaieyaphgnlldflrksrvletdpafaianstastlssqqllhfaadvargmdyl
sqkqfihrdlaarnilvgenyvakiadfglsrgqevyvkktmgrlpvrwmaieslnysvy
ttnsdvwsygvllweivslggtpycgmtcaelyeklpqgyrlekplncddevydlmrqcw
rekpyerpsfaqilvslnrmleerktyvnttlyekftyagid

Sequence, based on observed residues (ATOM records):

>d2oo8x_ d.144.1.7 (X:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
gqvlkarirmdaaikrmkekddhrdfagelevlcklghhpniinllgacehylaieyaph
gnlldflrksrvletdpafaianstastlssqqllhfaadvargmdylsqkqfihrdlaa
rnilvgenyvakiadfglmgrlpvrwmaieslnysvyttnsdvwsygvllweivslggtp
ycgmtcaelyeklpqgyrlekplncddevydlmrqcwrekpyerpsfaqilvslnrmlee
rktyvnttlyekftyagid

Timeline for d2oo8x_:

• d2oo8x_ first appeared in SCOPe 2.01
  
• d2oo8x_ appears in SCOPe 2.07