Lineage for d2on6a_ (2on6 A:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2125386Fold c.56: Phosphorylase/hydrolase-like [53162] (8 superfamilies)
    core: 3 layers, a/b/a ; mixed sheet of 5 strands: order 21354; strand 4 is antiparallel to the rest; contains crossover loops
  4. 2125403Superfamily c.56.2: Purine and uridine phosphorylases [53167] (2 families) (S)
    complex architecture; contains mixed beta-sheet of 8 strands, order 23415867, strands 3, 6 & 7 are antiparallel to the rest; and barrel, closed; n=5, S=8
  5. 2125404Family c.56.2.1: Purine and uridine phosphorylases [53168] (7 protein domains)
  6. 2125514Protein Purine nucleoside phosphorylase, PNP [53169] (12 species)
  7. 2125692Species Human (Homo sapiens) [TaxId:9606] [53170] (29 PDB entries)
    Uniprot P00491
  8. 2125702Domain d2on6a_: 2on6 A: [166765]
    automated match to d1ulaa_
    complexed with imh; mutant

Details for d2on6a_

PDB Entry: 2on6 (more details), 2.5 Å

PDB Description: Crystal stucture of human purine nucleoside phosphorylase mutant H257F with Imm-H
PDB Compounds: (A:) purine nucleoside phosphorylase

SCOPe Domain Sequences for d2on6a_:

Sequence, based on SEQRES records: (download)

>d2on6a_ c.56.2.1 (A:) Purine nucleoside phosphorylase, PNP {Human (Homo sapiens) [TaxId: 9606]}

Sequence, based on observed residues (ATOM records): (download)

>d2on6a_ c.56.2.1 (A:) Purine nucleoside phosphorylase, PNP {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d2on6a_:

Click to download the PDB-style file with coordinates for d2on6a_.
(The format of our PDB-style files is described here.)

Timeline for d2on6a_: