SCOPe 2.08: Domain d2o9ia_: 2o9i A:

Lineage for d2o9ia_ (2o9i A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Pregnane x receptor, PXR [63624] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [63625] (32 PDB entries)

8. Domain d2o9ia_: 2o9i A: [166590]
   automated match to d1m13a_
   complexed with 444

Details for d2o9ia_

PDB Entry: 2o9i, 2.8 Å

PDB Description: crystal structure of the human pregnane x receptor lbd in complex with an src-1 coactivator peptide and t0901317

PDB Compounds: (A:) orphan nuclear receptor pxr

SCOPe Domain Sequences for d2o9ia_:

Sequence, based on SEQRES records:

>d2o9ia_ a.123.1.1 (A:) Pregnane x receptor, PXR {Human (Homo sapiens) [TaxId: 9606]}
glteeqrmmirelmdaqmktfdttfshfknfrlpgvlssgcelpeslqapsreeaakwsq
vrkdlcslkvslqlrgedgsvwnykppadsggkeifsllphmadmstymfkgiisfakvi
syfrdlpiedqisllkgaafelsqlrfntvfnaetgtwecgrlsycledtaggfqqllle
pmlkfhymlkklqlheeeyvlmqaislfspdrpgvlqhrvvdqlqeqfaitlksyiecnr
pqpahrflflkimamltelrsinaqhtqrllriqdihpfatplmqelfgitg

Sequence, based on observed residues (ATOM records):

>d2o9ia_ a.123.1.1 (A:) Pregnane x receptor, PXR {Human (Homo sapiens) [TaxId: 9606]}
glteeqrmmirelmdaqmktfdttfshfknfrlpgvlsreeaakwsqvrkdlcslkvslq
lrgedgsvwnykppadsggkeifsllphmadmstymfkgiisfakvisyfrdlpiedqis
llkgaafelsqlrfntvfnaetgtwecgrlsycledtaggfqqlllepmlkfhymlkklq
lheeeyvlmqaislfspdrpgvlqhrvvdqlqeqfaitlksyiecnrpqpahrflflkim
amltelrsinaqhtqrllriqdihpfatplmqelfgitg

Timeline for d2o9ia_:

• d2o9ia_ first appeared in SCOPe 2.01
  
• d2o9ia_ appears in SCOPe 2.07