SCOPe 2.08: Domain d2j30a1: 2j30 A:29-277

Lineage for d2j30a1 (2j30 A:29-277)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.17: Caspase-like [52128] (1 superfamily)
   3 layers, a/b/a; core: mixed beta-sheet of 6 strands, order 213456, strand 6 is antiparallel to the rest

4. Superfamily c.17.1: Caspase-like [52129] (3 families)
   mature protein may be composed of two chains folded in a single domain

5. Family c.17.1.1: Caspase catalytic domain [52130] (8 proteins)

6. Protein Apopain (caspase-3, cpp32) [52131] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52132] (28 PDB entries)

8. Domain d2j30a1: 2j30 A:29-277 [165828]
   Other proteins in same PDB: d2j30a2
   automated match to d1nmqa_

Details for d2j30a1

PDB Entry: 2j30, 1.4 Å

PDB Description: the role of loop bundle hydrogen bonds in the maturation and activity of (pro)caspase-3

PDB Compounds: (A:) Caspase-3

SCOPe Domain Sequences for d2j30a1:

Sequence, based on SEQRES records:

>d2j30a1 c.17.1.1 (A:29-277) Apopain (caspase-3, cpp32) {Human (Homo sapiens) [TaxId: 9606]}
sgisldnsykmdypemglciiinnknfhkstgmtsrsgtdvdaanlretfrnlkyevrnk
ndltreeivelmrdvskedhskrssfvcvllshgeegiifgtngpvdlkkitnffrgdrc
rsltgkpklfiiqacrgteldcgietdsgvdddmachkipveadflyaystapgyyswrn
skdgswfiqslcamlkqyadklefmhiltrvnrkvatefesfsfdatfhakkqipcivsm
ltkelyfyh

Sequence, based on observed residues (ATOM records):

>d2j30a1 c.17.1.1 (A:29-277) Apopain (caspase-3, cpp32) {Human (Homo sapiens) [TaxId: 9606]}
sgisldnsykmdypemglciiinnknfhkstgmtsrsgtdvdaanlretfrnlkyevrnk
ndltreeivelmrdvskedhskrssfvcvllshgeegiifgtngpvdlkkitnffrgdrc
rsltgkpklfiiqacrgteldcgietddmachkipveadflyaystapgyyswrnskdgs
wfiqslcamlkqyadklefmhiltrvnrkvatefesfsfdatfhakkqipcivsmltkel
yfyh

Timeline for d2j30a1:

• d2j30a1 first appeared in SCOPe 2.01, called d2j30a_
  
• d2j30a1 appears in SCOPe 2.07