SCOPe 2.08: Domain d2ivsb1: 2ivs B:705-1012

Lineage for d2ivsb1 (2ivs B:705-1012)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (37 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1476 PDB entries)

8. Domain d2ivsb1: 2ivs B:705-1012 [165710]
   Other proteins in same PDB: d2ivsb2
   automated match to d1agwb_
   complexed with ack, fmt

Details for d2ivsb1

PDB Entry: 2ivs, 2 Å

PDB Description: crystal structure of non-phosphorylated ret tyrosine kinase domain

PDB Compounds: (B:) proto-oncogene tyrosine-protein kinase receptor ret

SCOPe Domain Sequences for d2ivsb1:

Sequence, based on SEQRES records:

>d2ivsb1 d.144.1.0 (B:705-1012) automated matches {Human (Homo sapiens) [TaxId: 9606]}
svdafkiledpkwefprknlvlgktlgegefgkvvkatafhlkgragyttvavkmlkena
spselrdllsefnvlkqvnhphviklygacsqdgpllliveyakygslrgflresrkvgp
gylgsggsrnsssldhpderaltmgdlisfawqisqgmqylaemklvhrdlaarnilvae
grkmkisdfglsrdvyeedsyvkrsqgripvkwmaieslfdhiyttqsdvwsfgvllwei
vtlggnpypgipperlfnllktghrmerpdncseemyrlmlqcwkqepdkrpvfadiskd
lekmmvkr

Sequence, based on observed residues (ATOM records):

>d2ivsb1 d.144.1.0 (B:705-1012) automated matches {Human (Homo sapiens) [TaxId: 9606]}
svdafkipkwefprknlvlgktlgegefgkvvkatafhlkgragyttvavkmlkenasps
elrdllsefnvlkqvnhphviklygacsqdgpllliveyakygslrgflresrkraltmg
dlisfawqisqgmqylaemklvhrdlaarnilvaegrkmkisdfglsrdvgripvkwmai
eslfdhiyttqsdvwsfgvllweivtlggnpypgipperlfnllktghrmerpdncseem
yrlmlqcwkqepdkrpvfadiskdlekmmvkr

Timeline for d2ivsb1:

• d2ivsb1 first appeared in SCOPe 2.01, called d2ivsb_
  
• d2ivsb1 appears in SCOPe 2.07