SCOPe 2.06: Domain d2i7va_: 2i7v A:

Lineage for d2i7va_ (2i7v A:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.157: Metallo-hydrolase/oxidoreductase [56280] (1 superfamily)
   duplication of beta(4)-alpha-beta-alpha motif; 4 layers a/b/b/a; mixed beta-sheets

4. Superfamily d.157.1: Metallo-hydrolase/oxidoreductase [56281] (15 families)

5. Family d.157.1.10: beta-CASP RNA-metabolising hydrolases [143927] (4 proteins)
   contains insertion of a single helicase-like alpha/beta domain (from (52540)) but without the P-loop motif

6. Protein Cleavage and polyadenylation specificity factor subunit 3 [160856] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [160857] (2 PDB entries)
   Uniprot Q9UKF6 9-459

8. Domain d2i7va_: 2i7v A: [165429]
   automated match to d2i7ta1
   complexed with so4, zn

Details for d2i7va_

PDB Entry: 2i7v, 2.1 Å

PDB Description: structure of human cpsf-73

PDB Compounds: (A:) Cleavage and polyadenylation specificity factor 73 kDa subunit

SCOPe Domain Sequences for d2i7va_:

Sequence, based on SEQRES records:

>d2i7va_ d.157.1.10 (A:) Cleavage and polyadenylation specificity factor subunit 3 {Human (Homo sapiens) [TaxId: 9606]}
eesdqllirplgagqevgrsciilefkgrkimldcgihpglegmdalpyidlidpaeidl
llishfhldhcgalpwflqktsfkgrtfmthatkaiyrwllsdyvkvsnisaddmlytet
dleesmdkietinfhevkevagikfwcyhaghvlgaamfmieiagvkllytgdfsrqedr
hlmaaeipnikpdiliiestygthihekreerearfcntvhdivnrggrglipvfalgra
qelllildeywqnhpelhdipiyyasslakkcmavyqtyvnamndkirkqininnpfvfk
hisnlksmdhfddigpsvvmaspgmmqsglsrelfeswctdkrngviiagycvegtlakh
imsepeeittmsgqklplkmsvdyisfsahtdyqqtsefiralkpphvilvhgeqnemar
lkaalireyedndevhievhnprnteavtlnfr

Sequence, based on observed residues (ATOM records):

>d2i7va_ d.157.1.10 (A:) Cleavage and polyadenylation specificity factor subunit 3 {Human (Homo sapiens) [TaxId: 9606]}
eesdqllirplgagqevgrsciilefkgrkimldcgihpglegmdalpyidlidpaeidl
llishfhldhcgalpwflqktsfkgrtfmthatkaiyrwllsdyvklytetdleesmdki
etinfhevkevagikfwcyhaghvlgaamfmieiagvkllytgdfsrqedrhlmaaeipn
ikpdiliiestygthihekreerearfcntvhdivnrggrglipvfalgraqelllilde
ywqnhpelhdipiyyasslakkcmavyqtyvnannpfvfkhisnlksmdhfddigpsvvm
aspgmmqsglsrelfeswctdkrngviiagycvegtlakhimsepeeittmsgqklplkm
svdyisfsahtdyqqtsefiralkpphvilvhgeqnemarlkaalireyedndevhievh
nprnteavtlnfr

Timeline for d2i7va_:

• d2i7va_ first appeared in SCOPe 2.01
  
• d2i7va_ appears in SCOPe 2.05
  
• d2i7va_ appears in SCOPe 2.07
  
• d2i7va_ appears in the current release, SCOPe 2.08