SCOPe 2.06: Domain d2i4qa1: 2i4q A:2-335

Lineage for d2i4qa1 (2i4q A:2-335)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.2: Pepsin-like [50646] (11 proteins)
   duplication: consists of two similar barrel domains
   N-terminal: barrel, partly opened; n*=6, S*=10

6. Protein Chymosin (synonym: renin) [50667] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50669] (76 PDB entries)

8. Domain d2i4qa1: 2i4q A:2-335 [165388]
   Other proteins in same PDB: d2i4qa2, d2i4qb2
   automated match to d1bila_
   complexed with ua4

Details for d2i4qa1

PDB Entry: 2i4q, 2.3 Å

PDB Description: Human renin/PF02342674 complex

PDB Compounds: (A:) renin

SCOPe Domain Sequences for d2i4qa1:

Sequence; same for both SEQRES and ATOM records:

>d2i4qa1 b.50.1.2 (A:2-335) Chymosin (synonym: renin) {Human (Homo sapiens) [TaxId: 9606]}
tssviltnymdtqyygeigigtppqtfkvvfdtgssnvwvpsskcsrlytacvyhklfda
sdsssykhngteltlrystgtvsgflsqdiitvggitvtqmfgevtempalpfmlaefdg
vvgmgfieqaigrvtpifdniisqgvlkedvfsfyynrdsensqslggqivlggsdpqhy
egnfhyinliktgvwqiqmkgvsvgsstllcedgclalvdtgasyisgstssieklmeal
gakkrlfdyvvkcnegptlpdisfhlggkeytltsadyvfqesysskklctlaihamdip
pptgptwalgatfirkfytefdrrnnrigfalar

Timeline for d2i4qa1:

• d2i4qa1 first appeared in SCOPe 2.01, called d2i4qa_
  
• d2i4qa1 was called d2i4qa_ in SCOPe 2.05
  
• d2i4qa1 appears in SCOPe 2.07
  
• d2i4qa1 appears in the current release, SCOPe 2.08