SCOPe 2.03: Domain d2i0ab_: 2i0a B:

Lineage for d2i0ab_ (2i0a B:)

1. Root: SCOPe 2.03

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 proteins)
   dimer of identical mono-domain chains, each containing (6,10) barrel

6. Protein Human immunodeficiency virus type 1 protease [50632] (8 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (421 PDB entries)
   Uniprot P35963 57-155 ! Uniprot P04587 69-167 ! Uniprot P03366 69-167 ! Uniprot P03367 69-167 ! Uniprot P03368 69-167

8. Domain d2i0ab_: 2i0a B: [165347]
   automated match to d1kzka_
   complexed with gol, mui, po4

Details for d2i0ab_

PDB Entry: 2i0a, 1.8 Å

PDB Description: crystal structure of kb-19 complexed with wild type hiv-1 protease

PDB Compounds: (B:) Protease

SCOPe Domain Sequences for d2i0ab_:

Sequence; same for both SEQRES and ATOM records:

>d2i0ab_ b.50.1.1 (B:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 [TaxId: 11676]}
pqitlwkrplvtiriggqlkealldtgaddtvleemnlpgkwkpkmiggiggfikvrqyd
qipieicghkaigtvlvgptpvniigrnlltqigctlnf

Timeline for d2i0ab_:

• d2i0ab_ first appeared in SCOPe 2.01
  
• d2i0ab_ appears in SCOPe 2.02
  
• d2i0ab_ appears in SCOPe 2.04
  
• d2i0ab_ appears in the current release, SCOPe 2.08