Lineage for d1le2a_ (1le2 A:)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2312794Fold a.24: Four-helical up-and-down bundle [47161] (28 superfamilies)
    core: 4 helices; bundle, closed or partly opened, left-handed twist; up-and-down
  4. 2312795Superfamily a.24.1: Apolipoprotein [47162] (1 family) (S)
  5. 2312796Family a.24.1.1: Apolipoprotein [47163] (2 proteins)
    Can exist in a coiled-coil oligomeric form, see PDB entry 1AV1
    family may also include the five-helical bundle protein Apolipophorin-III
  6. 2312797Protein Apolipoprotein E [88703] (3 species)
  7. 2312798Species Human (Homo sapiens), E2 [TaxId:9606] [47167] (2 PDB entries)
  8. 2312800Domain d1le2a_: 1le2 A: [16527]

Details for d1le2a_

PDB Entry: 1le2 (more details), 3 Å

PDB Description: structural basis for altered function in the common mutants of human apolipoprotein-e
PDB Compounds: (A:) apolipoprotein e2

SCOPe Domain Sequences for d1le2a_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1le2a_ a.24.1.1 (A:) Apolipoprotein E {Human (Homo sapiens), E2 [TaxId: 9606]}

SCOPe Domain Coordinates for d1le2a_:

Click to download the PDB-style file with coordinates for d1le2a_.
(The format of our PDB-style files is described here.)

Timeline for d1le2a_: