SCOPe 2.08: Domain d1nfna_: 1nfn A:

Lineage for d1nfna_ (1nfn A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.24: Four-helical up-and-down bundle [47161] (29 superfamilies)
   core: 4 helices; bundle, closed or partly opened, left-handed twist; up-and-down

4. Superfamily a.24.1: Apolipoprotein [47162] (1 family)

5. Family a.24.1.1: Apolipoprotein [47163] (2 proteins)
   Can exist in a coiled-coil oligomeric form, see PDB entry 1AV1
   family may also include the five-helical bundle protein Apolipophorin-III

6. Protein Apolipoprotein E [88703] (3 species)

7. Species Human (Homo sapiens), E3 [TaxId:9606] [47165] (7 PDB entries)

8. Domain d1nfna_: 1nfn A: [16523]

Details for d1nfna_

PDB Entry: 1nfn, 1.8 Å

PDB Description: apolipoprotein e3 (apoe3)

PDB Compounds: (A:) apolipoprotein e3

SCOPe Domain Sequences for d1nfna_:

Sequence, based on SEQRES records:

>d1nfna_ a.24.1.1 (A:) Apolipoprotein E {Human (Homo sapiens), E3 [TaxId: 9606]}
gqrwelalgrfwdylrwvqtlseqvqeellssqvtqelralmdetmkelkaykseleeql
tpvaeetrarlskelqaaqarlgadmedvcgrlvqyrgevqamlgqsteelrvrlashlr
klrkrllrdaddlqkrlavyqa

Sequence, based on observed residues (ATOM records):

>d1nfna_ a.24.1.1 (A:) Apolipoprotein E {Human (Homo sapiens), E3 [TaxId: 9606]}
gqrwelalgrfwdylrwvqtlseqvqeellssqvtqelralmdetmkelkaykseleeqr
lskelqaaqarlgadmedvcgrlvqyrgevqamlgqsteelrvrlashlrklrkrllrda
ddlqkrlavyqa

Timeline for d1nfna_:

• d1nfna_ first appeared (with stable ids) in SCOP 1.55, called d1nfn__
  
• d1nfna_ appears in SCOPe 2.07