SCOPe 2.06: Domain d1or3a_: 1or3 A:

Lineage for d1or3a_ (1or3 A:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.24: Four-helical up-and-down bundle [47161] (28 superfamilies)
   core: 4 helices; bundle, closed or partly opened, left-handed twist; up-and-down

4. Superfamily a.24.1: Apolipoprotein [47162] (1 family)

5. Family a.24.1.1: Apolipoprotein [47163] (1 protein)
   Can exist in a coiled-coil oligomeric form, see PDB entry 1AV1
   family may also include the five-helical bundle protein Apolipophorin-III

6. Protein Apolipoprotein E [88703] (3 species)

7. Species Human (Homo sapiens), E3 [TaxId:9606] [47165] (7 PDB entries)

8. Domain d1or3a_: 1or3 A: [16522]
   truncation mutant 165
   mutant

Details for d1or3a_

PDB Entry: 1or3, 1.73 Å

PDB Description: apolipoprotein e3 (apoe3), trigonal truncation mutant 165

PDB Compounds: (A:) protein (apolipoprotein e)

SCOPe Domain Sequences for d1or3a_:

Sequence, based on SEQRES records:

>d1or3a_ a.24.1.1 (A:) Apolipoprotein E {Human (Homo sapiens), E3 [TaxId: 9606]}
sgqrwelalgrfwdylrwvqtlseqvqeellssqvtqelralmdetmkelkaykseleeq
ltpvaeetrarlskelqaaqarlgadmedvcgrlvqyrgevqamlgqsteelrvrlashl
rklrkrllrdaddlqkrlavyqa

Sequence, based on observed residues (ATOM records):

>d1or3a_ a.24.1.1 (A:) Apolipoprotein E {Human (Homo sapiens), E3 [TaxId: 9606]}
sgqrwelalgrfwdylrwvqtlseqvqeellssqvtqelralmdetmkelkaykseleeq
ltarlskelqaaqarlgadmedvcgrlvqyrgevqamlgqsteelrvrlashlrklrkrl
lrdaddlqkrlavyqa

Timeline for d1or3a_:

• d1or3a_ first appeared (with stable ids) in SCOP 1.55
  
• d1or3a_ appears in SCOPe 2.05
  
• d1or3a_ appears in SCOPe 2.07
  
• d1or3a_ appears in the current release, SCOPe 2.08