SCOPe 2.01: Domain d2hgwb_: 2hgw B:

Lineage for d2hgwb_ (2hgw B:)

1. Root: SCOPe 2.01

2. Class e: Multi-domain proteins (alpha and beta) [56572] (66 folds)

3. Fold e.17: D-aminoacid aminotransferase-like PLP-dependent enzymes [56751] (1 superfamily)
   2 domains: (1) alpha+beta: beta3-alpha2-beta2; (2) alpha/beta, a part of its mixed sheet forms barrel: n=6, S=8

4. Superfamily e.17.1: D-aminoacid aminotransferase-like PLP-dependent enzymes [56752] (2 families)

5. Family e.17.1.1: D-aminoacid aminotransferase-like PLP-dependent enzymes [56753] (4 proteins)

6. Protein Branched-chain aminoacid aminotransferase [56757] (2 species)

7. Species Human (Homo sapiens), mitochondrial [TaxId:9606] [64508] (9 PDB entries)

8. Domain d2hgwb_: 2hgw B: [165106]
   automated match to d1ekfa_
   complexed with acy, epe, gol, plp, so4; mutant

Details for d2hgwb_

PDB Entry: 2hgw, 1.98 Å

PDB Description: crystal structure of cys318ala mutant of human mitochondrial branched chain aminotransferase

PDB Compounds: (B:) Branched-chain-amino-acid aminotransferase, mitochondrial

SCOPe Domain Sequences for d2hgwb_:

Sequence, based on SEQRES records:

>d2hgwb_ e.17.1.1 (B:) Branched-chain aminoacid aminotransferase {Human (Homo sapiens), mitochondrial [TaxId: 9606]}
asssfkaadlqlemtqkphkkpgpgeplvfgktftdhmlmvewndkgwgqpriqpfqnlt
lhpassslhyslqlfegmkafkgkdqqvrlfrpwlnmdrmlrsamrlclpsfdklellec
irrlievdkdwvpdaagtslyvrpvlignepslgvsqprrallfvilcpvgayfpggsvt
pvslladpafirawvggvgnyklggnygptvlvqqealkrgceqvlwlygpdhqltevgt
mnifvywthedgvlelvtpplngvilpgvvrqslldmaqtwgefrvvertitmkqllral
eegrvrevfgsgtacqvapvhrilykdrnlhiptmengpelilrfqkelkeiqygirahe
wmfpv

Sequence, based on observed residues (ATOM records):

>d2hgwb_ e.17.1.1 (B:) Branched-chain aminoacid aminotransferase {Human (Homo sapiens), mitochondrial [TaxId: 9606]}
asssfkaadlqlemtqkphkkpgpgeplvfgktftdhmlmvewndkgwgqpriqpfqnlt
lhpassslhyslqlfegmkafkgkdqqvrlfrpwlnmdrmlrsamrlclpsfdklellec
irrlievdkdwvpdaagtslyvrpvlignepslgvsqprrallfvilcpvgavtpvslla
dpafirawvggvgnyklggnygptvlvqqealkrgceqvlwlygpdhqltevgtmnifvy
wthedgvlelvtpplngvilpgvvrqslldmaqtwgefrvvertitmkqllraleegrvr
evfgsgtacqvapvhrilykdrnlhiptmengpelilrfqkelkeiqygirahewmfpv

Timeline for d2hgwb_:

• d2hgwb_ is new in SCOPe 2.01-stable
  
• d2hgwb_ appears in SCOPe 2.02
  
• d2hgwb_ appears in the current release, SCOPe 2.08