SCOPe 2.01: Domain d2fvlb_: 2fvl B:

Lineage for d2fvlb_ (2fvl B:)

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.7: NAD(P)-linked oxidoreductase [51430] (2 families)

5. Family c.1.7.1: Aldo-keto reductases (NADP) [51431] (16 proteins)
   Common fold covers whole protein structure

6. Protein automated matches [190169] (3 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188399] (33 PDB entries)

8. Domain d2fvlb_: 2fvl B: [164479]
   automated match to d1mrqa_
   complexed with nap

Details for d2fvlb_

PDB Entry: 2fvl, 2.4 Å

PDB Description: Crystal structure of human 3-alpha hydroxysteroid/dihydrodiol dehydrogenase (AKR1C4) complexed with NADP+

PDB Compounds: (B:) Aldo-keto reductase family 1, member C4

SCOPe Domain Sequences for d2fvlb_:

Sequence; same for both SEQRES and ATOM records:

>d2fvlb_ c.1.7.1 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mdpkyqrvelndghfmpvlgfgtyappevprnravevtklaieagfrhidsaylynneeq
vglairskiadgsvkredifytsklwctffqpqmvqpalesslkklqldyvdlyllhfpm
alkpgetplpkdengkvifdtvdlsatwevmekckdaglaksigvsnfnyrqlemilnkp
glkykpvcnqvechpylnqsklldfckskdivlvahsalgtqrhklwvdpnspvlledpv
lcalakkhkrtpalialryqlqrgvvvlaksyneqrireniqvfefqltsedmkvldgln
rnyryvvmdflmdhpdypfsdey

Timeline for d2fvlb_:

• d2fvlb_ is new in SCOPe 2.01-stable
  
• d2fvlb_ appears in SCOPe 2.02
  
• d2fvlb_ appears in the current release, SCOPe 2.08