SCOPe 2.08: Domain d2fszb_: 2fsz B:

Lineage for d2fszb_ (2fsz B:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Estrogen receptor beta [48521] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48522] (27 PDB entries)

8. Domain d2fszb_: 2fsz B: [164458]
   automated match to d1l2ja_
   complexed with oht

Details for d2fszb_

PDB Entry: 2fsz, 2.2 Å

PDB Description: a second binding site for hydroxytamoxifen within the coactivator- binding groove of estrogen receptor beta

PDB Compounds: (B:) Estrogen receptor beta

SCOPe Domain Sequences for d2fszb_:

Sequence, based on SEQRES records:

>d2fszb_ a.123.1.1 (B:) Estrogen receptor beta {Human (Homo sapiens) [TaxId: 9606]}
ldalspeqlvltlleaepphvlisrpsapfteasmmmsltkladkelvhmiswakkipgf
velslfdqvrllesswmevlmmglmwrsidhpgklifapdlvldrdegksvegileifdm
llattsrfrelklqhkeylcvkamillnssmyplvtatqdadssrklahllnavtdalvw
viaksgissqqqsmrlanllmllshvrhasnkgmehllnmksknvvpvydlllemlnahv
lr

Sequence, based on observed residues (ATOM records):

>d2fszb_ a.123.1.1 (B:) Estrogen receptor beta {Human (Homo sapiens) [TaxId: 9606]}
ldalspeqlvltlleaepphvlisrpsapfteasmmmsltkladkelvhmiswakkipgf
velslfdqvrllesswmevlmmglmwrsidhpgklifapdlvldrdegksvegileifdm
llattsrfrelklqhkeylcvkamillnssmsrklahllnavtdalvwviaksgissqqq
smrlanllmllshvrhasnkgmehllnmnvvpvydlllemlnahvlr

Timeline for d2fszb_:

• d2fszb_ first appeared in SCOPe 2.01
  
• d2fszb_ appears in SCOPe 2.07