SCOPe 2.05: Domain d2fstx_: 2fst X:

Lineage for d2fstx_ (2fst X:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (12 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (553 PDB entries)

8. Domain d2fstx_: 2fst X: [164456]
   automated match to d1a9ua_
   complexed with bog; mutant

Details for d2fstx_

PDB Entry: 2fst, 1.45 Å

PDB Description: mitogen activated protein kinase p38alpha (d176a+f327l) activating mutant

PDB Compounds: (X:) Mitogen-activated protein kinase 14

SCOPe Domain Sequences for d2fstx_:

Sequence, based on SEQRES records:

>d2fstx_ d.144.1.7 (X:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktglrvavkklsrpfqsiih
akrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcqkltd
dhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtademtgyva
trwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpga
ellkkissesarnyiqsltqmpkmnfanvfiganplavdllekmlvldsdkritaaqala
hayfaqyhdpddepvadpydqslesrdllidewksltydevisfvppp

Sequence, based on observed residues (ATOM records):

>d2fstx_ d.144.1.7 (X:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rptfyrqelnktiwevperyqnlspvggsvcaafdtktglrvavkklsrpfqsiihakrt
yrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnqkltddhvqfliyq
ilrglkyihsadiihrdlkpsnlavnedcelkildatrwyrapeimlnwmhynqtvdiws
vgcimaelltgrtlfpgtdhidqlklilrlvgtpgaellkkissesarnyiqsltqmpkm
nfanvfiganplavdllekmlvldsdkritaaqalahayfaqyhdpddepvadpydqsle
srdllidewksltydevisfvppp

Timeline for d2fstx_:

• d2fstx_ first appeared in SCOPe 2.01
  
• d2fstx_ appears in SCOPe 2.04
  
• d2fstx_ appears in SCOPe 2.06
  
• d2fstx_ appears in the current release, SCOPe 2.08