SCOPe 2.04: Domain d2fsox_: 2fso X:

Lineage for d2fsox_ (2fso X:)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (13 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (490 PDB entries)

8. Domain d2fsox_: 2fso X: [164455]
   automated match to d1a9ua_
   complexed with bog; mutant

Details for d2fsox_

PDB Entry: 2fso, 1.83 Å

PDB Description: mitogen activated protein kinase p38alpha (d176a) activating mutant

PDB Compounds: (X:) Mitogen-activated protein kinase 14

SCOPe Domain Sequences for d2fsox_:

Sequence, based on SEQRES records:

>d2fsox_ d.144.1.7 (X:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktglrvavkklsrpfqsiih
akrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcqkltd
dhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtademtgyva
trwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpga
ellkkissesarnyiqsltqmpkmnfanvfiganplavdllekmlvldsdkritaaqala
hayfaqyhdpddepvadpydqsfesrdllidewksltydevisfvpppl

Sequence, based on observed residues (ATOM records):

>d2fsox_ d.144.1.7 (X:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rptfyrqelnktiwevperyqnlspvgsgsvcaafdtktglrvavkklsrpfqsiihakr
tyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnkltddhvqfliyq
ilrglkyihsadiihrdlkpsnlavnedcelkildatrwyrapeimlnwmhynqtvdiws
vgcimaelltgrtlfpgtdhidqlklilrlvgtpgaellkkissesarnyiqsltqmpkm
nfanvfiganplavdllekmlvldsdkritaaqalahayfaqyhdpddepvadpydqsfe
srdllidewksltydevisfvpppl

Timeline for d2fsox_:

• d2fsox_ first appeared in SCOPe 2.01
  
• d2fsox_ appears in SCOPe 2.03
  
• d2fsox_ appears in SCOPe 2.05
  
• d2fsox_ appears in the current release, SCOPe 2.08