SCOPe 2.04: Domain d2fsmx_: 2fsm X:

Lineage for d2fsmx_ (2fsm X:)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (13 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (490 PDB entries)

8. Domain d2fsmx_: 2fsm X: [164454]
   automated match to d1a9ua_
   complexed with bog; mutant

Details for d2fsmx_

PDB Entry: 2fsm, 1.86 Å

PDB Description: mitogen activated protein kinase p38alpha (d176a+f327s) activating mutant form-b

PDB Compounds: (X:) Mitogen-activated protein kinase 14

SCOPe Domain Sequences for d2fsmx_:

Sequence, based on SEQRES records:

>d2fsmx_ d.144.1.7 (X:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
erptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktglrvavkklsrpfqsii
hakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcqklt
ddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtademtgyv
atrwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpg
aellkkissesarnyiqsltqmpkmnfanvfiganplavdllekmlvldsdkritaaqal
ahayfaqyhdpddepvadpydqssesrdllidewksltydevisfvppp

Sequence, based on observed residues (ATOM records):

>d2fsmx_ d.144.1.7 (X:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
erptfyrqelnktiwevperyqnlspvggsvcaafdtktglrvavkklsrpfqsiihakr
tyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnkltddhvqfliy
qilrglkyihsadiihrdlkpsnlavnedcelkildfatrwyrapeimlnwmhynqtvdi
wsvgcimaelltgrtlfpgtdhidqlklilrlvgtpgaellkkissesarnyiqsltqmp
kmnfanvfiganplavdllekmlvldsdkritaaqalahayfaqyhdpddepvadpydqs
sesrdllidewksltydevisfvppp

Timeline for d2fsmx_:

• d2fsmx_ first appeared in SCOPe 2.01
  
• d2fsmx_ appears in SCOPe 2.03
  
• d2fsmx_ appears in SCOPe 2.05
  
• d2fsmx_ appears in the current release, SCOPe 2.08