Lineage for d2fslx_ (2fsl X:)

  1. Root: SCOPe 2.04
  2. 1631855Class d: Alpha and beta proteins (a+b) [53931] (380 folds)
  3. 1671717Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1671718Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1671838Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1673984Protein automated matches [190091] (13 species)
    not a true protein
  7. 1674055Species Human (Homo sapiens) [TaxId:9606] [188447] (490 PDB entries)
  8. 1674130Domain d2fslx_: 2fsl X: [164453]
    automated match to d1a9ua_
    complexed with bog; mutant

Details for d2fslx_

PDB Entry: 2fsl (more details), 1.7 Å

PDB Description: mitogen activated protein kinase p38alpha (D176A+F327S) activating mutant form-A
PDB Compounds: (X:) Mitogen-activated protein kinase 14

SCOPe Domain Sequences for d2fslx_:

Sequence, based on SEQRES records: (download)

>d2fslx_ d.144.1.7 (X:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
erptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktglrvavkklsrpfqsii
hakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcqklt
ddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtademtgyv
atrwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpg
aellkkissesarnyiqsltqmpkmnfanvfiganplavdllekmlvldsdkritaaqal
ahayfaqyhdpddepvadpydqssesrdllidewksltydevisfvpppld

Sequence, based on observed residues (ATOM records): (download)

>d2fslx_ d.144.1.7 (X:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
erptfyrqelnktiwevperyqnlspvgsgagsvcaafdtktglrvavkklsrpfqsiih
akrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnqkltddhvq
fliyqilrglkyihsadiihrdlkpsnlavnedcelkildvatrwyrapeimlnwmhynq
tvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpgaellkkissesarnyiqsl
tqmpkmnfanvfiganplavdllekmlvldsdkritaaqalahayfaqyhdpddepvadp
ydqssesrdllidewksltydevisfvpppld

SCOPe Domain Coordinates for d2fslx_:

Click to download the PDB-style file with coordinates for d2fslx_.
(The format of our PDB-style files is described here.)

Timeline for d2fslx_: