Lineage for d2f6fa1 (2f6f A:1-298)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2116263Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423
  4. 2116264Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families) (S)
    share with the family I the common active site structure with a circularly permuted topology
  5. 2116365Family c.45.1.2: Higher-molecular-weight phosphotyrosine protein phosphatases [52805] (7 protein domains)
    has an extension to the beta-sheet of 3 antiparallel strands before strand 4
  6. 2116409Protein Tyrosine phosphatase [52806] (7 species)
  7. 2116410Species Human (Homo sapiens), 1B [TaxId:9606] [52807] (117 PDB entries)
    Uniprot P18031 2-300 ! Uniprot P18031 1-298 ! Uniprot P18031 2-299
  8. 2116431Domain d2f6fa1: 2f6f A:1-298 [164271]
    Other proteins in same PDB: d2f6fa2
    automated match to d1pa1a_
    complexed with cl, mg; mutant

Details for d2f6fa1

PDB Entry: 2f6f (more details), 2 Å

PDB Description: The structure of the S295F mutant of human PTP1B
PDB Compounds: (A:) Tyrosine-protein phosphatase, non-receptor type 1

SCOPe Domain Sequences for d2f6fa1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2f6fa1 c.45.1.2 (A:1-298) Tyrosine phosphatase {Human (Homo sapiens), 1B [TaxId: 9606]}

SCOPe Domain Coordinates for d2f6fa1:

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Timeline for d2f6fa1:

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