Lineage for d2f29b_ (2f29 B:)

  1. Root: SCOPe 2.01
  2. 929298Class b: All beta proteins [48724] (174 folds)
  3. 959648Fold b.68: 6-bladed beta-propeller [50938] (11 superfamilies)
    consists of six 4-stranded beta-sheet motifs; meander
  4. 959649Superfamily b.68.1: Sialidases [50939] (3 families) (S)
  5. 959650Family b.68.1.1: Sialidases (neuraminidases) [50940] (10 proteins)
  6. 959827Protein automated matches [190279] (4 species)
    not a true protein
  7. 959828Species Human (Homo sapiens) [TaxId:9606] [187077] (11 PDB entries)
  8. 959841Domain d2f29b_: 2f29 B: [164261]
    automated match to d1vcua_
    complexed with dan, epe; mutant

Details for d2f29b_

PDB Entry: 2f29 (more details), 2.92 Å

PDB Description: crystal structure of the human sialidase neu2 q116e mutant in complex with dana inhibitor
PDB Compounds: (B:) Sialidase 2

SCOPe Domain Sequences for d2f29b_:

Sequence, based on SEQRES records: (download)

>d2f29b_ b.68.1.1 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
maslpvlqkesvfqsgahayripallylpgqqsllafaeqraskkdehaelivlrrgdyd
apthqvqwqaqevvaqarldghrsmnpcplydaqtgtlflffiaipgqvteqqqletran
vtrlcqvtstdhgrtwssprdltdaaigpayrewstfavgpghclqlndrarslvvpaya
yrklhpiqrpipsafcflshdhgrtwarghfvaqdtlecqvaevetgeqrvvtlnarshl
rarvqaqstndgldfqesqlvkklvepppqgcqgsvisfpsprsgpgspaqwllythpth
swqradlgaylnprppapeawsepvllakgscaysdlqsmgtgpdgsplfgclyeandye
eivflmftlkqafpaey

Sequence, based on observed residues (ATOM records): (download)

>d2f29b_ b.68.1.1 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
maslpvlqkesvfqsgahayripallylpgqqsllafaeqraskkdehaelivlrrgdyd
apthqvqwqaqevvaqarldghrsmnpcplydaqtgtlflffiaipgqvteqqqletran
vtrlcqvtstdhgrtwssprdltdaaigpayrewstfavgpghclqlndrarslvvpaya
yrklhpiqrpipsafcflshdhgrtwarghfvaqdtlecqvaeveqrvvtlnarshlrar
vqaqstndgldfqesqlvkklvepppqgcqgsvisfpsprspaqwllythpthswqradl
gaylnprppapeawsepvllakgscaysdlqsmgtgpdgsplfgclyeandyeeivflmf
tlkqafpaey

SCOPe Domain Coordinates for d2f29b_:

Click to download the PDB-style file with coordinates for d2f29b_.
(The format of our PDB-style files is described here.)

Timeline for d2f29b_: