SCOPe 2.06: Domain d2e4oc_: 2e4o C:

Lineage for d2e4oc_ (2e4o C:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.128: Terpenoid synthases [48575] (1 superfamily)
   multihelical; core: 8 helices (C-J) are arranged in 2 parallel layers

4. Superfamily a.128.1: Terpenoid synthases [48576] (6 families)
   duplication: two metal-binding sites are related by a pseudo dyad that also relates helices C-F to helices G-J

5. Family a.128.1.4: Aristolochene/pentalenene synthase [48586] (3 proteins)

6. Protein automated matches [190618] (1 species)
   not a true protein

7. Species Aspergillus terreus [TaxId:33178] [187650] (16 PDB entries)

8. Domain d2e4oc_: 2e4o C: [163822]
   automated match to d1dgpa_
   complexed with bme, cl, mes

Details for d2e4oc_

PDB Entry: 2e4o, 2.2 Å

PDB Description: X-ray Crystal Structure of Aristolochene Synthase from Aspergillus terreus and the Evolution of Templates for the Cyclization of Farnesyl Diphosphate

PDB Compounds: (C:) Aristolochene synthase

SCOPe Domain Sequences for d2e4oc_:

Sequence, based on SEQRES records:

>d2e4oc_ a.128.1.4 (C:) automated matches {Aspergillus terreus [TaxId: 33178]}
slepppstfqplchplveevskevdgyflqhwnfpnekarkkfvaagfsrvtclyfpkal
ddrihfacrlltvlfliddlleymsfeegsayneklipisrgdvlpdrsipveyiiydlw
esmrahdremadeilepvflfmraqtdrtrarpmglggyleyrerdvgkellaalmrfsm
glklspselqrvreidancskhlsvvndiysyekelytsktahseggilctsvqilaqea
dvtaeaakrvlfvmcrewelrhqllvarlsaegletpglaayvegleyqmsgnelwsqtt
lrysv

Sequence, based on observed residues (ATOM records):

>d2e4oc_ a.128.1.4 (C:) automated matches {Aspergillus terreus [TaxId: 33178]}
slepppstfqplchplveevskevdgyflqhwnfpnekarkkfvaagfsrvtclyfpkal
ddrihfacrlltvlfliddlleymsfeegsayneklipisrgdvlpdrsipveyiiydlw
esmrahdremadeilepvflfmraqtdrtrarpmglggyleyrerdvgkellaalmrfsm
glklspselqrvreidancskhlsvvndiysyekelytilctsvqilaqeadvtaeaakr
vlfvmcrewelrhqllvarlsaegletpglaayvegleyqmsgnelwsqttlrysv

Timeline for d2e4oc_:

• d2e4oc_ first appeared in SCOPe 2.01
  
• d2e4oc_ appears in SCOPe 2.05
  
• d2e4oc_ appears in SCOPe 2.07
  
• d2e4oc_ appears in the current release, SCOPe 2.08