SCOPe 2.05: Domain d2e4oa_: 2e4o A:

Lineage for d2e4oa_ (2e4o A:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.128: Terpenoid synthases [48575] (1 superfamily)
   multihelical; core: 8 helices (C-J) are arranged in 2 parallel layers

4. Superfamily a.128.1: Terpenoid synthases [48576] (6 families)
   duplication: two metal-binding sites are related by a pseudo dyad that also relates helices C-F to helices G-J

5. Family a.128.1.4: Aristolochene/pentalenene synthase [48586] (3 proteins)

6. Protein automated matches [190618] (1 species)
   not a true protein

7. Species Aspergillus terreus [TaxId:33178] [187650] (11 PDB entries)

8. Domain d2e4oa_: 2e4o A: [163820]
   automated match to d1dgpa_
   complexed with bme, cl, mes

Details for d2e4oa_

PDB Entry: 2e4o, 2.2 Å

PDB Description: X-ray Crystal Structure of Aristolochene Synthase from Aspergillus terreus and the Evolution of Templates for the Cyclization of Farnesyl Diphosphate

PDB Compounds: (A:) Aristolochene synthase

SCOPe Domain Sequences for d2e4oa_:

Sequence, based on SEQRES records:

>d2e4oa_ a.128.1.4 (A:) automated matches {Aspergillus terreus [TaxId: 33178]}
slepppstfqplchplveevskevdgyflqhwnfpnekarkkfvaagfsrvtclyfpkal
ddrihfacrlltvlfliddlleymsfeegsayneklipisrgdvlpdrsipveyiiydlw
esmrahdremadeilepvflfmraqtdrtrarpmglggyleyrerdvgkellaalmrfsm
glklspselqrvreidancskhlsvvndiysyekelytsktahseggilctsvqilaqea
dvtaeaakrvlfvmcrewelrhqllvarlsaegletpglaayvegleyqmsgnelwsqtt
lrysv

Sequence, based on observed residues (ATOM records):

>d2e4oa_ a.128.1.4 (A:) automated matches {Aspergillus terreus [TaxId: 33178]}
slepppstfqplchplveevskevdgyflqhwnfpnekarkkfvaagfsrvtclyfpkal
ddrihfacrlltvlfliddlleymsfeegsayneklipisrgdvlpdrsipveyiiydlw
esmrahdremadeilepvflfmraqtdrtrarpmglggyleyrerdvgkellaalmrfsm
glklspselqrvreidancskhlsvvndiysyekelytlctsvqilaqeadvtaeaakrv
lfvmcrewelrhqllvarlsaegletpglaayvegleyqmsgnelwsqttlrysv

Timeline for d2e4oa_:

• d2e4oa_ first appeared in SCOPe 2.01
  
• d2e4oa_ appears in SCOPe 2.04
  
• d2e4oa_ appears in SCOPe 2.06
  
• d2e4oa_ appears in the current release, SCOPe 2.08