SCOPe 2.08: Domain d2e2ba1: 2e2b A:229-502

Lineage for d2e2ba1 (2e2b A:229-502)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (850 PDB entries)

8. Domain d2e2ba1: 2e2b A:229-502 [163805]
   Other proteins in same PDB: d2e2ba2, d2e2bb2
   automated match to d1opjb_
   complexed with 406

Details for d2e2ba1

PDB Entry: 2e2b, 2.2 Å

PDB Description: Crystal structure of the c-Abl kinase domain in complex with INNO-406

PDB Compounds: (A:) Proto-oncogene tyrosine-protein kinase ABL1

SCOPe Domain Sequences for d2e2ba1:

Sequence, based on SEQRES records:

>d2e2ba1 d.144.1.7 (A:229-502) automated matches {Human (Homo sapiens) [TaxId: 9606]}
spnydkwemertditmkhklgggqygevyegvwkkysltvavktlkedtmeveeflkeaa
vmkeikhpnlvqllgvctreppfyiitefmtygnlldylrecnrqevnavvllymatqis
sameylekknfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfpikwtap
eslaynkfsiksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpegcpekv
yelmracwqwnpsdrpsfaeihqafetmfqessi

Sequence, based on observed residues (ATOM records):

>d2e2ba1 d.144.1.7 (A:229-502) automated matches {Human (Homo sapiens) [TaxId: 9606]}
spnydkwemertditmkhklgggqygevyegvwkkysltvavktlmeveeflkeaavmke
ikhpnlvqllgvctreppfyiitefmtygnlldylrecnrqevnavvllymatqissame
ylekknfihrdlaarnclvgenhlvkvadfglsrltytahagakfpikwtapeslaynkf
siksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpegcpekvyelmracw
qwnpsdrpsfaeihqafetmfqessi

Timeline for d2e2ba1:

• d2e2ba1 first appeared in SCOPe 2.01, called d2e2ba_
  
• d2e2ba1 appears in SCOPe 2.07