SCOPe 2.08: Domain d2e01a1: 2e01 A:1-453

Lineage for d2e01a1 (2e01 A:1-453)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (24 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.1: Papain-like [54002] (26 proteins)

6. Protein Bleomycin hydrolase [54017] (2 species)
   DNA-binding protease that has more insertions in the papain-like fold

7. Species Baker's yeast (Saccharomyces cerevisiae), Gal6 [TaxId:4932] [54018] (9 PDB entries)

8. Domain d2e01a1: 2e01 A:1-453 [163772]
   Other proteins in same PDB: d2e01a2
   automated match to d1a6ra_
   mutant
   has additional subdomain(s) that are not in the common domain
   has additional insertions and/or extensions that are not grouped together

Details for d2e01a1

PDB Entry: 2e01, 1.73 Å

PDB Description: crystal structure of h369a mutant of yeast bleomycin hydrolase

PDB Compounds: (A:) Cysteine proteinase 1

SCOPe Domain Sequences for d2e01a1:

Sequence, based on SEQRES records:

>d2e01a1 d.3.1.1 (A:1-453) Bleomycin hydrolase {Baker's yeast (Saccharomyces cerevisiae), Gal6 [TaxId: 4932]}
msssidiskinswnkefqsdlthqlattvlknynaddallnktrlqkqdnrvfntvvstd
stpvtnqkssgrcwlfaatnqlrlnvlselnlkefelsqaylffydklekanyfldqivs
sadqdidsrlvqyllaaptedggqysmflnlvkkyglipkdlygdlpysttasrkwnsll
ttklrefaetlrtalkersaddsiivtlreqmqreifrlmslfmdippvqpneqftweyv
dkdkkihtikstplefaskyakldpstpvslindprhpygklikidrlgnvlggdaviyl
nvdnetlsklvvkrlqnnkavffgshtpkfmdkktgvmdielwnypaigynlpqqkasri
ryheslmtaamlitgchvdetsklplryrvenswgkdsgkdglyvmtqkyfeeycfqivv
dinelpkelaskftsgkeepivlpiwdpmgala

Sequence, based on observed residues (ATOM records):

>d2e01a1 d.3.1.1 (A:1-453) Bleomycin hydrolase {Baker's yeast (Saccharomyces cerevisiae), Gal6 [TaxId: 4932]}
msssidiskinswnkefqsdlthqlattvlknynaddallnktrlqkqdnrvfntvvsgr
cwlfaatnqlrlnvlselnlkefelsqaylffydklekanyfldqivssadqdidsrlvq
yllaaptedggqysmflnlvkkyglipkdlygdlpysttasrkwnsllttklrefaetlr
talkersaddsiivtlreqmqreifrlmslfmdippvqpneqftweyvdkdkkihtikst
plefaskyakldpstpvslindprhpygklikidrlgnvlggdaviylnvdnetlsklvv
krlqnnkavffgshtpkfmdkktgvmdielwnypaigynlpqqkasriryheslmtaaml
itgchvdetsklplryrvenswgkdsgkdglyvmtqkyfeeycfqivvdinelpkelask
ftsgkeepivlpiwdpmgala

Timeline for d2e01a1:

• d2e01a1 first appeared in SCOPe 2.01, called d2e01a_
  
• d2e01a1 appears in SCOPe 2.07