Lineage for d2ciga_ (2cig A:)

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2477518Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest
  4. 2477519Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families) (S)
  5. 2477520Family c.71.1.1: Dihydrofolate reductases [53598] (4 proteins)
  6. 2477549Protein Dihydrofolate reductase, prokaryotic type [53599] (8 species)
  7. 2477682Species Mycobacterium tuberculosis [TaxId:1773] [53602] (9 PDB entries)
  8. 2477685Domain d2ciga_: 2cig A: [163414]
    automated match to d1df7a_
    complexed with 1dg, gol, so4

Details for d2ciga_

PDB Entry: 2cig (more details), 1.9 Å

PDB Description: dihydrofolate reductase from mycobacterium tuberculosis inhibited by the acyclic 4r isomer of inh-nadp a derivative of the prodrug isoniazid.
PDB Compounds: (A:) dihydrofolate reductase

SCOPe Domain Sequences for d2ciga_:

Sequence; same for both SEQRES and ATOM records: (download)

>d2ciga_ c.71.1.1 (A:) Dihydrofolate reductase, prokaryotic type {Mycobacterium tuberculosis [TaxId: 1773]}

SCOPe Domain Coordinates for d2ciga_:

Click to download the PDB-style file with coordinates for d2ciga_.
(The format of our PDB-style files is described here.)

Timeline for d2ciga_: