Lineage for d2c6eb_ (2c6e B:)

  1. Root: SCOPe 2.04
  2. 1631855Class d: Alpha and beta proteins (a+b) [53931] (380 folds)
  3. 1671717Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1671718Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1671838Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1673984Protein automated matches [190091] (13 species)
    not a true protein
  7. 1674055Species Human (Homo sapiens) [TaxId:9606] [188447] (490 PDB entries)
  8. 1674282Domain d2c6eb_: 2c6e B: [163266]
    automated match to d1ol5a_
    complexed with hpm; mutant

Details for d2c6eb_

PDB Entry: 2c6e (more details), 2.1 Å

PDB Description: aurora a kinase activated mutant (t287d) in complex with a 5-aminopyrimidinyl quinazoline inhibitor
PDB Compounds: (B:) serine/threonine-protein kinase 6

SCOPe Domain Sequences for d2c6eb_:

Sequence, based on SEQRES records: (download)

>d2c6eb_ d.144.1.7 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qwaledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlrreveiqs
hlrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitelanalsy
chskrvihrdikpenlllgsagelkiadfgwsvhapssrrtdlcgtldylppemiegrmh
dekvdlwslgvlcyeflvgkppfeantyqetykrisrveftfpdfvtegardlisrllkh
npsqrpmlrevlehpwitanss

Sequence, based on observed residues (ATOM records): (download)

>d2c6eb_ d.144.1.7 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qwaledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlrreveiqs
hlrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitelanalsy
chskrvihrdikpenlllgsagelkiadgtldylppemiegrmhdekvdlwslgvlcyef
lvgkppfeantyqetykrisrveftfpdfvtegardlisrllkhnpsqrpmlrevlehpw
itanss

SCOPe Domain Coordinates for d2c6eb_:

Click to download the PDB-style file with coordinates for d2c6eb_.
(The format of our PDB-style files is described here.)

Timeline for d2c6eb_: