SCOPe 2.01: Domain d2bksb_: 2bks B:

Lineage for d2bksb_ (2bks B:)

1. Root: SCOPe 2.01

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.2: Pepsin-like [50646] (11 proteins)
   duplication: consists of two similar barrel domains
   N-terminal: barrel, partly opened; n*=6, S*=10

6. Protein Chymosin (synonym: renin) [50667] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50669] (40 PDB entries)

8. Domain d2bksb_: 2bks B: [163117]
   automated match to d1bila_
   complexed with pz1

Details for d2bksb_

PDB Entry: 2bks, 2.2 Å

PDB Description: crystal structure of renin-pf00074777 complex

PDB Compounds: (B:) renin

SCOPe Domain Sequences for d2bksb_:

Sequence, based on SEQRES records:

>d2bksb_ b.50.1.2 (B:) Chymosin (synonym: renin) {Human (Homo sapiens) [TaxId: 9606]}
ssviltnymdtqyygeigigtppqtfkvvfdtgssnvwvpsskcsrlytacvyhklfdas
dsssykhngteltlrystgtvsgflsqdiitvggitvtqmfgevtempalpfmlaefdgv
vgmgfieqaigrvtpifdniisqgvlkedvfsfyynrdsensqslggqivlggsdpqhye
gnfhyinliktgvwqiqmkgvsvgsstllcedgclalvdtgasyisgstssieklmealg
akkrlfdyvvkcnegptlpdisfhlggkeytltsadyvfqesysskklctlaihamdipp
ptgptwalgatfirkfytefdrrnnrigfalar

Sequence, based on observed residues (ATOM records):

>d2bksb_ b.50.1.2 (B:) Chymosin (synonym: renin) {Human (Homo sapiens) [TaxId: 9606]}
ssviltnymdtqyygeigigtppqtfkvvfdtgssnvwvpsskcsrlytacvyhklfdas
dsssykhngteltlrystgtvsgflsqdiitvggitvtqmfgevtempalpfmlaefdgv
vgmgfieqaigrvtpifdniisqgvlkedvfsfyynrdsenlggqivlggsdpqhyegnf
hyinliktgvwqiqmkgvsvgsstllcedgclalvdtgasyisgstssieklmealgakk
rlfdyvvkcnegptlpdisfhlggkeytltsadyvfqesysskklctlaihamdippptg
ptwalgatfirkfytefdrrnnrigfalar

Timeline for d2bksb_:

• d2bksb_ is new in SCOPe 2.01-stable
  
• d2bksb_ appears in SCOPe 2.02
  
• d2bksb_ appears in the current release, SCOPe 2.08