SCOPe 2.08: Domain d2bfxb_: 2bfx B:

Lineage for d2bfxb_ (2bfx B:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species African clawed frog (Xenopus laevis) [TaxId:8355] [187456] (11 PDB entries)

8. Domain d2bfxb_: 2bfx B: [163066]
   automated match to d1ol5a_

Details for d2bfxb_

PDB Entry: 2bfx, 1.8 Å

PDB Description: mechanism of aurora-b activation by incenp and inhibition by hesperadin.

PDB Compounds: (B:) aurora kinase b-a

SCOPe Domain Sequences for d2bfxb_:

Sequence, based on SEQRES records:

>d2bfxb_ d.144.1.7 (B:) automated matches {African clawed frog (Xenopus laevis) [TaxId: 8355]}
talaempkrkftiddfdigrplgkgkfgnvylarekqnkfimalkvlfksqlekegvehq
lrreieiqshlrhpnilrmynyfhdrkriylmlefaprgelykelqkhgrfdeqrsatfm
eeladalhycherkvihrdikpenllmgykgelkiadfgwsvhapslrrrtmcgtldylp
pemiegkthdekvdlwcagvlcyeflvgmppfdspshtethrrivnvdlkfppflsdgsk
dliskllryhppqrlplkgvmehpwvkansrrvlppvyqs

Sequence, based on observed residues (ATOM records):

>d2bfxb_ d.144.1.7 (B:) automated matches {African clawed frog (Xenopus laevis) [TaxId: 8355]}
talaempkrkftiddfdigrplgkgnvylarekqnkfimalkvlfksqlekegvehqlrr
eieiqshlrhpnilrmynyfhdrkriylmlefaprgelykelqkhgrfdeqrsatfmeel
adalhycherkvihrdikpenllmgykgelkiadfgwsvhapslrrrtmcgtldylppem
iegkthdekvdlwcagvlcyeflvgmppfdspshtethrrivnvdlkfppflsdgskdli
skllryhppqrlplkgvmehpwvkansrrvlppvyqs

Timeline for d2bfxb_:

• d2bfxb_ first appeared in SCOPe 2.01
  
• d2bfxb_ appears in SCOPe 2.07