Lineage for d2bboa_ (2bbo A:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2109203Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. 2109204Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families) (S)
    division into families based on beta-sheet topologies
  5. 2112785Family c.37.1.12: ABC transporter ATPase domain-like [52686] (25 protein domains)
    there are two additional subdomains inserted into the central core that has a RecA-like topology
  6. 2112801Protein Cystic fibrosis transmembrane conductance regulator, CFTR, nucleotide-binding domain [102378] (2 species)
  7. 2112802Species Human (Homo sapiens) [TaxId:9606] [117543] (9 PDB entries)
    Uniprot P13569 389-671
  8. 2112820Domain d2bboa_: 2bbo A: [163031]
    automated match to d1xmja_
    complexed with atp, mg

Details for d2bboa_

PDB Entry: 2bbo (more details), 2.55 Å

PDB Description: human nbd1 with phe508
PDB Compounds: (A:) Cystic fibrosis transmembrane conductance regulator

SCOPe Domain Sequences for d2bboa_:

Sequence, based on SEQRES records: (download)

>d2bboa_ c.37.1.12 (A:) Cystic fibrosis transmembrane conductance regulator, CFTR, nucleotide-binding domain {Human (Homo sapiens) [TaxId: 9606]}
ttevvmenvtafweegfgellekakqnnnnrktsngddslsfsnlsllgtpvlkdinfki
ergqllavagstgagktsllmmimgelepsegkikhsgrisfcsqfswimpgtikeniif
gvsydeyryrsvikacqleediskfaekdnivlgeggitlsegqqakislaravykdadl
ylldspfgyldvltekeifescvcklmanktrilvtskmehlkkadkililhegssyfyg
tfselqnlqpdfssklmgcdsfdqfsaerrnsiltetlrrfslegdap

Sequence, based on observed residues (ATOM records): (download)

>d2bboa_ c.37.1.12 (A:) Cystic fibrosis transmembrane conductance regulator, CFTR, nucleotide-binding domain {Human (Homo sapiens) [TaxId: 9606]}
ttevvmenvtafweeglgtpvlkdinfkiergqllavagstgagktsllmmimgelepse
gkikhsgrisfcsqfswimpgtikeniifgvsydeyryrsvikacqleediskfaekdni
vlgeggitlsegqqakislaravykdadlylldspfgyldvltekeifescvcklmankt
rilvtskmehlkkadkililhegssyfygtfselqnlqpdfssklmsfdqfsaerrnsil
tetlrrfslegdap

SCOPe Domain Coordinates for d2bboa_:

Click to download the PDB-style file with coordinates for d2bboa_.
(The format of our PDB-style files is described here.)

Timeline for d2bboa_: