Lineage for d2avvd_ (2avv D:)

  1. Root: SCOPe 2.01
  2. 929298Class b: All beta proteins [48724] (174 folds)
  3. 955287Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 955288Superfamily b.50.1: Acid proteases [50630] (4 families) (S)
  5. 955289Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 proteins)
    dimer of identical mono-domain chains, each containing (6,10) barrel
  6. 955305Protein Human immunodeficiency virus type 1 protease [50632] (5 species)
  7. 955367Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (378 PDB entries)
    Uniprot P35963 57-155 ! Uniprot P04587 69-167 ! Uniprot P03366 69-167 ! Uniprot P03367 69-167 ! Uniprot P03368 69-167
  8. 955507Domain d2avvd_: 2avv D: [162925]
    automated match to d1fgcc_
    complexed with acy, cl, mk1; mutant

Details for d2avvd_

PDB Entry: 2avv (more details), 1.5 Å

PDB Description: kinetics, stability, and structural changes in high resolution crystal structures of hiv-1 protease with drug resistant mutations l24i, i50v, and g73s
PDB Compounds: (D:) Pol polyprotein

SCOPe Domain Sequences for d2avvd_:

Sequence; same for both SEQRES and ATOM records: (download)

>d2avvd_ b.50.1.1 (D:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 [TaxId: 11676]}
pqitlwkrplvtikiggqlkealldtgaddtvieemslpgrwkpkmiggiggfikvrqyd
qiiieiaghkaistvlvgptpvniigrnlltqigatlnf

SCOPe Domain Coordinates for d2avvd_:

Click to download the PDB-style file with coordinates for d2avvd_.
(The format of our PDB-style files is described here.)

Timeline for d2avvd_: