SCOPe 2.08: Domain d2aazi_: 2aaz I:

Lineage for d2aazi_ (2aaz I:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
   contains large mixed beta-sheet

4. Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (2 families)
   automatically mapped to Pfam PF00303

5. Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (4 proteins)

6. Protein automated matches [190469] (17 species)
   not a true protein

7. Species Fungus (Filobasidiella neoformans) [TaxId:5207] [187389] (1 PDB entry)

8. Domain d2aazi_: 2aaz I: [162739]
   automated match to d1ci7a_
   complexed with cb3, ump

Details for d2aazi_

PDB Entry: 2aaz, 2.08 Å

PDB Description: cryptococcus neoformans thymidylate synthase complexed with substrate and an antifolate

PDB Compounds: (I:) Thymidylate synthase

SCOPe Domain Sequences for d2aazi_:

Sequence, based on SEQRES records:

>d2aazi_ d.117.1.1 (I:) automated matches {Fungus (Filobasidiella neoformans) [TaxId: 5207]}
pdheeyqyldlirriinvgevrpdrtgtgtvalfappsfrfsladntlpllttkrvflrg
viaellwfvsgctdakmlssqgvgiwdgngskeflekvglghrregdlgpvygfqwrhfg
aeytdadgdykgkgvdqlqrvidtiknnptdrriilsawnpkdlplmalppchmfcqffv
slppadspgskpklsclmyqrscdlglgvpfniasyallthmialitdtephefilqmgd
ahvyrdhveplktqlereprdfpklkwarskeeigdidgfkvedfvvegykpwgkidmkm
sa

Sequence, based on observed residues (ATOM records):

>d2aazi_ d.117.1.1 (I:) automated matches {Fungus (Filobasidiella neoformans) [TaxId: 5207]}
pdheeyqyldlirriinvgevrpdrtgtgtvalfappsfrfsladntlpllttkrvflrg
viaellwfvsgctdakmlssqgvgiwdgngskeflekvglghrregdlgpvygfqwrhfg
aeytdadgdykgkgvdqlqrvidtiknnptdrriilsawnpkdlplmalppchmfcqffv
slpppgskpklsclmyqrscdlglgvpfniasyallthmialitdtephefilqmgdahv
yrdhveplktqlereprdfpklkwarskeeigdidgfkvedfvvegykpwgkidmkmsa

Timeline for d2aazi_:

• d2aazi_ first appeared in SCOPe 2.01
  
• d2aazi_ appears in SCOPe 2.07