SCOPe 2.05: Domain d2a3ia_: 2a3i A:

Lineage for d2a3ia_ (2a3i A:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187214] (138 PDB entries)

8. Domain d2a3ia_: 2a3i A: [162659]
   automated match to d1m2za_
   complexed with c0r

Details for d2a3ia_

PDB Entry: 2a3i, 1.95 Å

PDB Description: structural and biochemical mechanisms for the specificity of hormone binding and coactivator assembly by mineralocorticoid receptor

PDB Compounds: (A:) Mineralocorticoid receptor

SCOPe Domain Sequences for d2a3ia_:

Sequence; same for both SEQRES and ATOM records:

>d2a3ia_ a.123.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
raltpspvmvleniepeivyagydsskpdtaenllstlnrlagkqmiqvvkwakvlpgfk
nlpledqitliqyswmslssfalswrsykhtnsqflyfapdlvfneekmhqsamyelcqg
mhqislqfvrlqltfeeytimkvllllstipkdglksqaafeemrtnyikelrkmvtkcp
nnsgqswqrfyqltklldsmhdlvsdllefcfytfreshalkvefpamlveiisdqlpkv
esgnakplyfhrk

Timeline for d2a3ia_:

• d2a3ia_ first appeared in SCOPe 2.01
  
• d2a3ia_ appears in SCOPe 2.04
  
• d2a3ia_ appears in SCOPe 2.06
  
• d2a3ia_ appears in the current release, SCOPe 2.08