Lineage for d2a2ka_ (2a2k A:)

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2455196Fold c.46: Rhodanese/Cell cycle control phosphatase [52820] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 5 strands, order 32451
  4. 2455197Superfamily c.46.1: Rhodanese/Cell cycle control phosphatase [52821] (5 families) (S)
    Pfam PF00581
    the active site structure is similar to those of the families I and II protein phosphatases; the topology can be related by a different circular permutation to the family I topology
  5. 2455198Family c.46.1.1: Cell cycle control phosphatase, catalytic domain [52822] (5 proteins)
  6. 2455202Protein CDC25b [52825] (1 species)
  7. 2455203Species Human (Homo sapiens) [TaxId:9606] [52826] (14 PDB entries)
  8. 2455204Domain d2a2ka_: 2a2k A: [162658]
    automated match to d1cwra_
    complexed with cl, so4; mutant

Details for d2a2ka_

PDB Entry: 2a2k (more details), 1.52 Å

PDB Description: Crystal Structure of an active site mutant, C473S, of Cdc25B Phosphatase Catalytic Domain
PDB Compounds: (A:) M-phase inducer phosphatase 2

SCOPe Domain Sequences for d2a2ka_:

Sequence, based on SEQRES records: (download)

>d2a2ka_ c.46.1.1 (A:) CDC25b {Human (Homo sapiens) [TaxId: 9606]}

Sequence, based on observed residues (ATOM records): (download)

>d2a2ka_ c.46.1.1 (A:) CDC25b {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d2a2ka_:

Click to download the PDB-style file with coordinates for d2a2ka_.
(The format of our PDB-style files is described here.)

Timeline for d2a2ka_: