SCOPe 2.05: Domain d2a1ab_: 2a1a B:

Lineage for d2a1ab_ (2a1a B:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (21 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (615 PDB entries)

8. Domain d2a1ab_: 2a1a B: [162648]
   Other proteins in same PDB: d2a1aa1, d2a1aa2
   automated match to d2java1

Details for d2a1ab_

PDB Entry: 2a1a, 2.8 Å

PDB Description: pkr kinase domain-eif2alpha complex

PDB Compounds: (B:) Interferon-induced, double-stranded RNA-activated protein kinase

SCOPe Domain Sequences for d2a1ab_:

Sequence, based on SEQRES records:

>d2a1ab_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
gahtvdkrfgmdfkeieligsggfgqvfkakhridgktyvikrvkynnekaerevkalak
ldhvnivhyngcwdgfdydpetssknssrsktkclfiqmefcdkgtleqwiekrrgekld
kvlalelfeqitkgvdyihskklinrdlkpsniflvdtkqvkigdfglvtslkndgkrtr
skgtlrymspeqissqdygkevdlyalglilaellhvcdtafetskfftdlrdgiisdif
dkkektllqkllskkpedrpntseilrtltvwkk

Sequence, based on observed residues (ATOM records):

>d2a1ab_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
gahtvdkrfgmdfkeieligsggfgqvfkakhridgktyvikrvkynnekaerevkalak
ldhvnivhyngcwdgfdydpetssrsktkclfiqmefcdkgtleqwiekrrgekldkvla
lelfeqitkgvdyihskklinrdlkpsniflvdtkqvkigdfglvtslkndgkrtrskgt
lrymspeqissqdygkevdlyalglilaellhvcdtafetskfftdlrdgiisdifdkke
ktllqkllskkpedrpntseilrtltvwkk

Timeline for d2a1ab_:

• d2a1ab_ first appeared in SCOPe 2.01
  
• d2a1ab_ appears in SCOPe 2.04
  
• d2a1ab_ is called d2a1ab1 in SCOPe 2.06
  
• d2a1ab_ appears in the current release, SCOPe 2.08, called d2a1ab1