SCOPe 2.04: Domain d2a19b_: 2a19 B:

Lineage for d2a19b_ (2a19 B:)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (19 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (476 PDB entries)

8. Domain d2a19b_: 2a19 B: [162646]
   Other proteins in same PDB: d2a19a1, d2a19a2
   automated match to d2java1
   complexed with anp, mg, po4

Details for d2a19b_

PDB Entry: 2a19, 2.5 Å

PDB Description: pkr kinase domain- eif2alpha- amp-pnp complex.

PDB Compounds: (B:) Interferon-induced, double-stranded RNA-activated protein kinase

SCOPe Domain Sequences for d2a19b_:

Sequence, based on SEQRES records:

>d2a19b_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ahtvdkrfgmdfkeieligsggfgqvfkakhridgktyvikrvkynnekaerevkalakl
dhvnivhyngcwdgfdydpetssknssrsktkclfiqmefcdkgtleqwiekrrgekldk
vlalelfeqitkgvdyihskklinrdlkpsniflvdtkqvkigdfglvtslkndgkrtrs
kgtlrymspeqissqdygkevdlyalglilaellhvcdtafetskfftdlrdgiisdifd
kkektllqkllskkpedrpntseilrtltvwkk

Sequence, based on observed residues (ATOM records):

>d2a19b_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ahtvdkrfgmdfkeieligsggfgqvfkakhridgktyvikrvkynnekaerevkalakl
dhvnivhyngcwdgfdydrsktkclfiqmefcdkgtleqwiekrrgekldkvlalelfeq
itkgvdyihskklinrdlkpsniflvdtkqvkigdfglvtslkndgkrtrskgtlrymsp
eqissqdygkevdlyalglilaellhvcdtafetskfftdlrdgiisdifdkkektllqk
llskkpedrpntseilrtltvwkk

Timeline for d2a19b_:

• d2a19b_ first appeared in SCOPe 2.01
  
• d2a19b_ appears in SCOPe 2.03
  
• d2a19b_ appears in SCOPe 2.05
  
• d2a19b_ appears in the current release, SCOPe 2.08, called d2a19b1