SCOPe 2.05: Domain d1zrka_: 1zrk A:

Lineage for d1zrka_ (1zrk A:)

1. Root: SCOPe 2.05

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (49 proteins)

6. Protein Coagulation factor XI [117237] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [117238] (32 PDB entries)
   Uniprot P03951 388-624

8. Domain d1zrka_: 1zrk A: [162575]
   automated match to d1xx9b_
   complexed with 367, so4

Details for d1zrka_

PDB Entry: 1zrk, 2.3 Å

PDB Description: factor xi complexed with 3-hydroxypropyl 3-(7-amidinonaphthalene-1- carboxamido)benzenesulfonate

PDB Compounds: (A:) Coagulation factor XI

SCOPe Domain Sequences for d1zrka_:

Sequence; same for both SEQRES and ATOM records:

>d1zrka_ b.47.1.2 (A:) Coagulation factor XI {Human (Homo sapiens) [TaxId: 9606]}
ivggtasvrgewpwqvtlhttsptqrhlcggsiignqwiltaahcfygvespkilrvysg
ilnqseiaedtsffgvqeiiihdqykmaesgydiallklettvnytdsqrpislpskgdr
nviytdcwvtgwgyrklrdkiqntlqkakiplvtneecqkryrghkithkmicagyregg
kdackgdsggplsckhnevwhlvgitswgegcaqrerpgvytnvveyvdwilektqa

Timeline for d1zrka_:

• d1zrka_ first appeared in SCOPe 2.01
  
• d1zrka_ appears in SCOPe 2.04
  
• d1zrka_ appears in SCOPe 2.06
  
• d1zrka_ appears in the current release, SCOPe 2.08